Swine fever virus purification and - concentration

Swine fever virus solutions contng undesired proteins are subjected to fractional precipitation with solutions (pref. 50% solns) of polyethylene glycol (mol. wt. pref. 1000-2000), pref. at pH 7-9 (esp 8.5) and at between 0 degree C and room temp. (pref. ca 4-5 degrees C). The process yields a fracti...

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Bibliographische Detailangaben
Hauptverfasser:	ARMBRUSTER,OTTO,DR, WAGNER,OTTO,DR, CARMENES,PEDRO,DR, BATLORIA GUALBA,LA
Format:	Patent
Sprache:	eng ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Swine fever virus solutions contng undesired proteins are subjected to fractional precipitation with solutions (pref. 50% solns) of polyethylene glycol (mol. wt. pref. 1000-2000), pref. at pH 7-9 (esp 8.5) and at between 0 degree C and room temp. (pref. ca 4-5 degrees C). The process yields a fraction consisting of practically pure virus antigen and a small amount of polyethylene glycol (other fractions contain only inert protein). which can be stored and/or converted into vaccines which are more active and less allergenic than commercial vaccines.