Preparation of 4-methylacetophenone, used as intermediate in synthesis of agrochemicals and pharmaceuticals, by reacting p-tolyl-magnesium halide in ether and acetic anhydride at a set temperature

Preparation of isomer-pure 4-methylacetophenone (I) comprises reacting p-tolyl-magnesium halide (II) in suitable ethers with acetic anhydride (III) at -40 to +10 deg C, then working the reaction solution up in a suitable way and separating (I). Verfahren zur Herstellung von isomerenreinem 4-Methylac...

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Hauptverfasser: SCHERER, STEFAN, TETZLAFF, HERRIBERT, MEUDT, ANDREAS, VOLLMUELLER, FRANK, KAUTZ, HEINZ GEORG
Format: Patent
Sprache:eng ; ger
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