VERFAHREN ZUR HERSTELLUNG HETEROCYCLISCHER NITROMETHANDERIVATE

The invention concerns novel heterocyclic nitromethane derivatives of the formula 1 as defined hereinafter (and their non-toxic salts) wherein the heterocyclic moiety Q may bear a wide variety of optional substituents, together with pharmaceutical compositions containing them. The nitromethane deriv...

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Hauptverfasser:	PRESTON,JOHN,GB, COOPER,ANTHONY L.,GB, LONGRIDGE,JETHRO L.,GB, BROWN,STEVEN P.,GB, MORRIS,JEFFREY J.,GB
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Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	PRESTON,JOHN,GB COOPER,ANTHONY L.,GB LONGRIDGE,JETHRO L.,GB BROWN,STEVEN P.,GB MORRIS,JEFFREY J.,GB
description	The invention concerns novel heterocyclic nitromethane derivatives of the formula 1 as defined hereinafter (and their non-toxic salts) wherein the heterocyclic moiety Q may bear a wide variety of optional substituents, together with pharmaceutical compositions containing them. The nitromethane derivatives are inhibitors of the enzyme aldose reductase and are of value in the treatment of certain complications of diabetes and galactosemia. The invention further concerns novel processes for the manufacture and use of said inhibitors.
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title	VERFAHREN ZUR HERSTELLUNG HETEROCYCLISCHER NITROMETHANDERIVATE
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