PYRROLYLBENZODIAZEPINONES, PROCESSES OF THEIR PREPARATION AND MEDICAMENTS BASED THEREON

PYRROLYLBENZODIAZEPINONES, PROCESSES OF THEIR PREPARATION AND MEDICAMENTS BASED THEREON

The present invention relates to compounds of the formula wherein R is methyl, fluorine or bromine, and pharmaceutically acceptable salts thereof. Utilizable as therapeutically active agents especially for the treatment of retroviral infections, particularly HIV infections, they can be prepared in a...

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Bibliographische Detailangaben
1. Verfasser: MINGU HSU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to compounds of the formula wherein R is methyl, fluorine or bromine, and pharmaceutically acceptable salts thereof. Utilizable as therapeutically active agents especially for the treatment of retroviral infections, particularly HIV infections, they can be prepared in a manner known per se by a process which comprises reacting 2-bromo-2'-(1H-pyrrol-2-yl-carbonyl)acetanilide, correspondingly substituted by R in the 4'-position, with ammonia and cyclizing the obtained 2-aminoacetanilide with pivalic acid.