Process for preparing 2-(4-methoxycarbonylpyrazol-1-yl)adenosine and 2-(4-ethoxycarbonylpyrazol-1-yl)adenosine

Zpusob prípravy 2-(4-methoxykarbonylpyrazol-1-yl)adenosinu vzorce Ia a 2-(4-ethoxykarbonylpyrazol-1-yl)adenosinu vzorce Ib reakcí 2-hydrazinoadenosinu vzorce III a sodné soli 3,3-dimethoxy-2-methoxykarbonylpropen-1-olu vzorce Va nebo sodné soli 3,3-diethoxy-2-ethoxykarbonylpropen-1-olu vzorce Vb v k...

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Hauptverfasser: DVORAKOVA BARBORA, KVAPIL LUBOMIR, HRADIL PAVEL, GREPL MARTIN, SLUZAR PETR
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KVAPIL LUBOMIR
HRADIL PAVEL
GREPL MARTIN
SLUZAR PETR
description Zpusob prípravy 2-(4-methoxykarbonylpyrazol-1-yl)adenosinu vzorce Ia a 2-(4-ethoxykarbonylpyrazol-1-yl)adenosinu vzorce Ib reakcí 2-hydrazinoadenosinu vzorce III a sodné soli 3,3-dimethoxy-2-methoxykarbonylpropen-1-olu vzorce Va nebo sodné soli 3,3-diethoxy-2-ethoxykarbonylpropen-1-olu vzorce Vb v kombinaci s rozpoustedlem a kyselým cinidlem. A method for the preparation of 2-(4-methoxycarbonylpyrazol-1-yl)adenosine of formula 1a and 2-(4-ethoxycarbonylpyrazol-1-yl)adenosine of formula 1b by reaction of 2-hydrazinoadenosine of formula III and the sodium salt of 3,3-dimethoxy-2-methoxycarbonylpropen-1-ol of formula Va or the sodium salt of 3,3-diethoxy-2-ethoxycarbonylpropen-1-ol of formula Vb in combination with a solvent and an acidic agent.
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A method for the preparation of 2-(4-methoxycarbonylpyrazol-1-yl)adenosine of formula 1a and 2-(4-ethoxycarbonylpyrazol-1-yl)adenosine of formula 1b by reaction of 2-hydrazinoadenosine of formula III and the sodium salt of 3,3-dimethoxy-2-methoxycarbonylpropen-1-ol of formula Va or the sodium salt of 3,3-diethoxy-2-ethoxycarbonylpropen-1-ol of formula Vb in combination with a solvent and an acidic agent.</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
title Process for preparing 2-(4-methoxycarbonylpyrazol-1-yl)adenosine and 2-(4-ethoxycarbonylpyrazol-1-yl)adenosine
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