PROCESS FOR PREPARING (1S,4R)- OR (1R,4S)-4-(2-AMINO-6-CHLORO-9-H-PURIN-9-YL)-2-CYKLOPENTENE-1-METHANOL
Racemic or optically active 1-amino-4-(hydroxymethyl)-2- cyclopentene derivatives are obtained by acylation of 1-amino-2-cyclopentene-4- carboxylic acid with an acid halide, followed by reduction of the carboxyl group. A method for the production of racemic or optically active 4-(hydroxymethyl)-2-cy...
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creator | BURGDORF KURT ETTER KAY-SARA DUC LAURENT DR BRIEDEN WALTER DR BERNEGGER CHRISTINE DR BOSSARD PIERRE DR URBAN EVA MARIA BIRCH OLWEN MARY DR BRUX FRANK O MURCHU COLM DR GUGGISBERG YVES DR GORDON JOHN |
description | Racemic or optically active 1-amino-4-(hydroxymethyl)-2- cyclopentene derivatives are obtained by acylation of 1-amino-2-cyclopentene-4- carboxylic acid with an acid halide, followed by reduction of the carboxyl group. A method for the production of racemic or optically active 4-(hydroxymethyl)-2-cyclopentene derivatives of formula (XIII) involves acylation of a cyclopentene-4-carboxylic acid derivative of formula (XIV) (as the racemate or an optically active isomer) with a carboxylic acid halide of formula R1>-CO-X (XI), followed by reduction of the resulting acid derivative (XV): [Image] R1>1-4C alkyl, 1-4C alkoxy, aryl or aryloxy; X : halogen. |
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A method for the production of racemic or optically active 4-(hydroxymethyl)-2-cyclopentene derivatives of formula (XIII) involves acylation of a cyclopentene-4-carboxylic acid derivative of formula (XIV) (as the racemate or an optically active isomer) with a carboxylic acid halide of formula R1>-CO-X (XI), followed by reduction of the resulting acid derivative (XV): [Image] R1>1-4C alkyl, 1-4C alkoxy, aryl or aryloxy; X : halogen.</description><edition>6</edition><language>cze ; eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PROCESSES USING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19981216&DB=EPODOC&CC=CZ&NR=145898A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19981216&DB=EPODOC&CC=CZ&NR=145898A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BURGDORF KURT</creatorcontrib><creatorcontrib>ETTER KAY-SARA</creatorcontrib><creatorcontrib>DUC LAURENT DR</creatorcontrib><creatorcontrib>BRIEDEN WALTER DR</creatorcontrib><creatorcontrib>BERNEGGER CHRISTINE DR</creatorcontrib><creatorcontrib>BOSSARD PIERRE DR</creatorcontrib><creatorcontrib>URBAN EVA MARIA</creatorcontrib><creatorcontrib>BIRCH OLWEN MARY DR</creatorcontrib><creatorcontrib>BRUX FRANK</creatorcontrib><creatorcontrib>O MURCHU COLM DR</creatorcontrib><creatorcontrib>GUGGISBERG YVES DR</creatorcontrib><creatorcontrib>GORDON JOHN</creatorcontrib><title>PROCESS FOR PREPARING (1S,4R)- OR (1R,4S)-4-(2-AMINO-6-CHLORO-9-H-PURIN-9-YL)-2-CYKLOPENTENE-1-METHANOL</title><description>Racemic or optically active 1-amino-4-(hydroxymethyl)-2- cyclopentene derivatives are obtained by acylation of 1-amino-2-cyclopentene-4- carboxylic acid with an acid halide, followed by reduction of the carboxyl group. A method for the production of racemic or optically active 4-(hydroxymethyl)-2-cyclopentene derivatives of formula (XIII) involves acylation of a cyclopentene-4-carboxylic acid derivative of formula (XIV) (as the racemate or an optically active isomer) with a carboxylic acid halide of formula R1>-CO-X (XI), followed by reduction of the resulting acid derivative (XV): [Image] R1>1-4C alkyl, 1-4C alkoxy, aryl or aryloxy; X : halogen.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1998</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFi7EOgjAURVkcjPoNdiwJbyhUA2PTFEssbfOKAy6EmOpilAT_PzK4O92Tk3PXycOjkyoEUjskHpUX2NgToSxkHFMgi6UMMx5S4EBzEG1jHRxBauPQQQUa_GW5LNSbFHKQ_dk4r2ynrAIGreq0sM5sk9V9fM5x99tNsq9VJzXE6T3EeRpv8RU_g7wyfiirUhTF_-ILAOcyrw</recordid><startdate>19981216</startdate><enddate>19981216</enddate><creator>BURGDORF KURT</creator><creator>ETTER KAY-SARA</creator><creator>DUC LAURENT DR</creator><creator>BRIEDEN WALTER DR</creator><creator>BERNEGGER CHRISTINE DR</creator><creator>BOSSARD PIERRE DR</creator><creator>URBAN EVA MARIA</creator><creator>BIRCH OLWEN MARY DR</creator><creator>BRUX FRANK</creator><creator>O MURCHU COLM DR</creator><creator>GUGGISBERG YVES DR</creator><creator>GORDON JOHN</creator><scope>EVB</scope></search><sort><creationdate>19981216</creationdate><title>PROCESS FOR PREPARING (1S,4R)- OR (1R,4S)-4-(2-AMINO-6-CHLORO-9-H-PURIN-9-YL)-2-CYKLOPENTENE-1-METHANOL</title><author>BURGDORF KURT ; ETTER KAY-SARA ; DUC LAURENT DR ; BRIEDEN WALTER DR ; BERNEGGER CHRISTINE DR ; BOSSARD PIERRE DR ; URBAN EVA MARIA ; BIRCH OLWEN MARY DR ; BRUX FRANK ; O MURCHU COLM DR ; GUGGISBERG YVES DR ; GORDON JOHN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CZ145898A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>cze ; eng</language><creationdate>1998</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>BURGDORF KURT</creatorcontrib><creatorcontrib>ETTER KAY-SARA</creatorcontrib><creatorcontrib>DUC LAURENT DR</creatorcontrib><creatorcontrib>BRIEDEN WALTER DR</creatorcontrib><creatorcontrib>BERNEGGER CHRISTINE DR</creatorcontrib><creatorcontrib>BOSSARD PIERRE DR</creatorcontrib><creatorcontrib>URBAN EVA MARIA</creatorcontrib><creatorcontrib>BIRCH OLWEN MARY DR</creatorcontrib><creatorcontrib>BRUX FRANK</creatorcontrib><creatorcontrib>O MURCHU COLM DR</creatorcontrib><creatorcontrib>GUGGISBERG YVES DR</creatorcontrib><creatorcontrib>GORDON JOHN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BURGDORF KURT</au><au>ETTER KAY-SARA</au><au>DUC LAURENT DR</au><au>BRIEDEN WALTER DR</au><au>BERNEGGER CHRISTINE DR</au><au>BOSSARD PIERRE DR</au><au>URBAN EVA MARIA</au><au>BIRCH OLWEN MARY DR</au><au>BRUX FRANK</au><au>O MURCHU COLM DR</au><au>GUGGISBERG YVES DR</au><au>GORDON JOHN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING (1S,4R)- OR (1R,4S)-4-(2-AMINO-6-CHLORO-9-H-PURIN-9-YL)-2-CYKLOPENTENE-1-METHANOL</title><date>1998-12-16</date><risdate>1998</risdate><abstract>Racemic or optically active 1-amino-4-(hydroxymethyl)-2- cyclopentene derivatives are obtained by acylation of 1-amino-2-cyclopentene-4- carboxylic acid with an acid halide, followed by reduction of the carboxyl group. A method for the production of racemic or optically active 4-(hydroxymethyl)-2-cyclopentene derivatives of formula (XIII) involves acylation of a cyclopentene-4-carboxylic acid derivative of formula (XIV) (as the racemate or an optically active isomer) with a carboxylic acid halide of formula R1>-CO-X (XI), followed by reduction of the resulting acid derivative (XV): [Image] R1>1-4C alkyl, 1-4C alkoxy, aryl or aryloxy; X : halogen.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PROCESSES USING MICROORGANISMS SPIRITS VINEGAR WINE |
title | PROCESS FOR PREPARING (1S,4R)- OR (1R,4S)-4-(2-AMINO-6-CHLORO-9-H-PURIN-9-YL)-2-CYKLOPENTENE-1-METHANOL |
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