ΠΑΡΑΓΩΓΑ 4-(ΑΡΥΛ)-(ΑΡΥΛΟΞΥ)ΜΕΘΥΛΟΠΙΠΕΡΙΔΙΝΗΣ ΚΑΙ Η ΧΡΗΣΗ ΤΟΥΣ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΕΠΑΝΑΠΡΟΣΛΗΨΗΣ ΣΕΡΟΤΟΝΙΝΗΣ ΚΑΙ/Ή ΝΟΡΑΔΡΕΝΑΛΙΝΗΣ
Νέες 4-υποκατεστημένες πιπεριδίνες του γενικού τύπου (I) περιγράφονται New 4-substituted piperidines of general formula (I) are described in which groups R1 and R2 are non-substituted aryl radicals or aryl radicals mono- or poly-substituted with halogen (fluorine, chlorine, bromine, iodine), alkyl,...
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| creator | PUMAR DURAN CARMEN ORJALES VENERO AURELIO TOLEDO AVELLO ANTONIO |
| description | Νέες 4-υποκατεστημένες πιπεριδίνες του γενικού τύπου (I) περιγράφονται
New 4-substituted piperidines of general formula (I) are described in which groups R1 and R2 are non-substituted aryl radicals or aryl radicals mono- or poly-substituted with halogen (fluorine, chlorine, bromine, iodine), alkyl, alkoxy, cyano, trifluoromethoxy, trifluoromethyl, benzoyl, phenyl, nitro, amino, aminoalkyl, aminoaryl and carbonylamino. These compounds, and their pharmaceutically acceptable salts, inhibit serotonin and/or noradrenaline reuptake, and are useful as antidepressants. Other potential therapeutic applications of these compounds are treatment of nervous bulimia, obsessive-compulsive disorders, alcohol addiction, anxiety, panic, pain, pre-menstrual syndrome and social phobia, as well as migraine prophylaxis. |
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New 4-substituted piperidines of general formula (I) are described in which groups R1 and R2 are non-substituted aryl radicals or aryl radicals mono- or poly-substituted with halogen (fluorine, chlorine, bromine, iodine), alkyl, alkoxy, cyano, trifluoromethoxy, trifluoromethyl, benzoyl, phenyl, nitro, amino, aminoalkyl, aminoaryl and carbonylamino. These compounds, and their pharmaceutically acceptable salts, inhibit serotonin and/or noradrenaline reuptake, and are useful as antidepressants. Other potential therapeutic applications of these compounds are treatment of nervous bulimia, obsessive-compulsive disorders, alcohol addiction, anxiety, panic, pain, pre-menstrual syndrome and social phobia, as well as migraine prophylaxis.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNT00OwUAU7sZCcIex00VDg4R1QxygG6tGZKwECZewbGiqqlqhwWW-S7iIbwaRWFl8b16-n_feFI0HMvg4ERvcCV-0rJpmcsTmt0WKI3ITBwTYvYkMERHQEGFLJAhxFtgzEwmEAldKpFR7oT9X6l0Vn16fgmJjTogUGehTlJAxl1KOmb69hp71nlQnkp9ddawFiVR_Y8sa6Cnxx1Y2CpPRdCkr77dkVPs91xlYcjH35HIxGsuZXHnO0LYbnW677bp28x_PE6ynsAM</recordid><startdate>20140702</startdate><enddate>20140702</enddate><creator>PUMAR DURAN CARMEN</creator><creator>ORJALES VENERO AURELIO</creator><creator>TOLEDO AVELLO ANTONIO</creator><scope>EVB</scope></search><sort><creationdate>20140702</creationdate><title>ΠΑΡΑΓΩΓΑ 4-(ΑΡΥΛ)-(ΑΡΥΛΟΞΥ)ΜΕΘΥΛΟΠΙΠΕΡΙΔΙΝΗΣ ΚΑΙ Η ΧΡΗΣΗ ΤΟΥΣ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΕΠΑΝΑΠΡΟΣΛΗΨΗΣ ΣΕΡΟΤΟΝΙΝΗΣ ΚΑΙ/Ή ΝΟΡΑΔΡΕΝΑΛΙΝΗΣ</title><author>PUMAR DURAN CARMEN ; ORJALES VENERO AURELIO ; TOLEDO AVELLO ANTONIO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CY1108955TT13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>Greek</language><creationdate>2014</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PUMAR DURAN CARMEN</creatorcontrib><creatorcontrib>ORJALES VENERO AURELIO</creatorcontrib><creatorcontrib>TOLEDO AVELLO ANTONIO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PUMAR DURAN CARMEN</au><au>ORJALES VENERO AURELIO</au><au>TOLEDO AVELLO ANTONIO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ΠΑΡΑΓΩΓΑ 4-(ΑΡΥΛ)-(ΑΡΥΛΟΞΥ)ΜΕΘΥΛΟΠΙΠΕΡΙΔΙΝΗΣ ΚΑΙ Η ΧΡΗΣΗ ΤΟΥΣ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΕΠΑΝΑΠΡΟΣΛΗΨΗΣ ΣΕΡΟΤΟΝΙΝΗΣ ΚΑΙ/Ή ΝΟΡΑΔΡΕΝΑΛΙΝΗΣ</title><date>2014-07-02</date><risdate>2014</risdate><abstract>Νέες 4-υποκατεστημένες πιπεριδίνες του γενικού τύπου (I) περιγράφονται
New 4-substituted piperidines of general formula (I) are described in which groups R1 and R2 are non-substituted aryl radicals or aryl radicals mono- or poly-substituted with halogen (fluorine, chlorine, bromine, iodine), alkyl, alkoxy, cyano, trifluoromethoxy, trifluoromethyl, benzoyl, phenyl, nitro, amino, aminoalkyl, aminoaryl and carbonylamino. These compounds, and their pharmaceutically acceptable salts, inhibit serotonin and/or noradrenaline reuptake, and are useful as antidepressants. Other potential therapeutic applications of these compounds are treatment of nervous bulimia, obsessive-compulsive disorders, alcohol addiction, anxiety, panic, pain, pre-menstrual syndrome and social phobia, as well as migraine prophylaxis.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ΠΑΡΑΓΩΓΑ 4-(ΑΡΥΛ)-(ΑΡΥΛΟΞΥ)ΜΕΘΥΛΟΠΙΠΕΡΙΔΙΝΗΣ ΚΑΙ Η ΧΡΗΣΗ ΤΟΥΣ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΕΠΑΝΑΠΡΟΣΛΗΨΗΣ ΣΕΡΟΤΟΝΙΝΗΣ ΚΑΙ/Ή ΝΟΡΑΔΡΕΝΑΛΙΝΗΣ |
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