ANTICUERPOS BIESPECÍFICOS Y MÉTODO DE FABRICACIÓN DE LOS MISMOS
La invención se refiere a anticuerpos monoclonales biespecíficos bivalentes (bbmAb) o sus variantes, y a métodos de fabricación de dichos anticuerpos mediante la coexpresión de derivados mutados Fc modificados, de dos anticuerpos monoclonales diferentes, en líneas celulares de mamíferos. The inventi...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | spa |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Graf, Christian Jostock, Thomas Oliver, Stephen John Knopf, Hans-Peter Kovarik, Jiri Heitmann, Daniel Koheler, Rolf Buch, Tina Woisetschlaeger, Maximilian Bardroff, Michael Otto Patel, Dhavalkumar |
| description | La invención se refiere a anticuerpos monoclonales biespecíficos bivalentes (bbmAb) o sus variantes, y a métodos de fabricación de dichos anticuerpos mediante la coexpresión de derivados mutados Fc modificados, de dos anticuerpos monoclonales diferentes, en líneas celulares de mamíferos.
The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CU20190100A7</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CU20190100A7</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CU20190100A73</originalsourceid><addsrcrecordid>eNrjZHBy9AvxdA51DQrwD1Zw8nQNDnB1Ptzr5ukM5EYq-B7uDPF38VdwcVVwc3QK8nR2dPY8PNkPxPcBKvD1DPb1D-ZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOoUYGhpYGhgYGjubGxKgBAAZKLUM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ANTICUERPOS BIESPECÍFICOS Y MÉTODO DE FABRICACIÓN DE LOS MISMOS</title><source>esp@cenet</source><creator>Graf, Christian ; Jostock, Thomas ; Oliver, Stephen John ; Knopf, Hans-Peter ; Kovarik, Jiri ; Heitmann, Daniel ; Koheler, Rolf ; Buch, Tina ; Woisetschlaeger, Maximilian ; Bardroff, Michael Otto ; Patel, Dhavalkumar</creator><creatorcontrib>Graf, Christian ; Jostock, Thomas ; Oliver, Stephen John ; Knopf, Hans-Peter ; Kovarik, Jiri ; Heitmann, Daniel ; Koheler, Rolf ; Buch, Tina ; Woisetschlaeger, Maximilian ; Bardroff, Michael Otto ; Patel, Dhavalkumar</creatorcontrib><description>La invención se refiere a anticuerpos monoclonales biespecíficos bivalentes (bbmAb) o sus variantes, y a métodos de fabricación de dichos anticuerpos mediante la coexpresión de derivados mutados Fc modificados, de dos anticuerpos monoclonales diferentes, en líneas celulares de mamíferos.
The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines.</description><language>spa</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201130&DB=EPODOC&CC=CU&NR=20190100A7$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201130&DB=EPODOC&CC=CU&NR=20190100A7$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Graf, Christian</creatorcontrib><creatorcontrib>Jostock, Thomas</creatorcontrib><creatorcontrib>Oliver, Stephen John</creatorcontrib><creatorcontrib>Knopf, Hans-Peter</creatorcontrib><creatorcontrib>Kovarik, Jiri</creatorcontrib><creatorcontrib>Heitmann, Daniel</creatorcontrib><creatorcontrib>Koheler, Rolf</creatorcontrib><creatorcontrib>Buch, Tina</creatorcontrib><creatorcontrib>Woisetschlaeger, Maximilian</creatorcontrib><creatorcontrib>Bardroff, Michael Otto</creatorcontrib><creatorcontrib>Patel, Dhavalkumar</creatorcontrib><title>ANTICUERPOS BIESPECÍFICOS Y MÉTODO DE FABRICACIÓN DE LOS MISMOS</title><description>La invención se refiere a anticuerpos monoclonales biespecíficos bivalentes (bbmAb) o sus variantes, y a métodos de fabricación de dichos anticuerpos mediante la coexpresión de derivados mutados Fc modificados, de dos anticuerpos monoclonales diferentes, en líneas celulares de mamíferos.
The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBy9AvxdA51DQrwD1Zw8nQNDnB1Ptzr5ukM5EYq-B7uDPF38VdwcVVwc3QK8nR2dPY8PNkPxPcBKvD1DPb1D-ZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOoUYGhpYGhgYGjubGxKgBAAZKLUM</recordid><startdate>20201130</startdate><enddate>20201130</enddate><creator>Graf, Christian</creator><creator>Jostock, Thomas</creator><creator>Oliver, Stephen John</creator><creator>Knopf, Hans-Peter</creator><creator>Kovarik, Jiri</creator><creator>Heitmann, Daniel</creator><creator>Koheler, Rolf</creator><creator>Buch, Tina</creator><creator>Woisetschlaeger, Maximilian</creator><creator>Bardroff, Michael Otto</creator><creator>Patel, Dhavalkumar</creator><scope>EVB</scope></search><sort><creationdate>20201130</creationdate><title>ANTICUERPOS BIESPECÍFICOS Y MÉTODO DE FABRICACIÓN DE LOS MISMOS</title><author>Graf, Christian ; Jostock, Thomas ; Oliver, Stephen John ; Knopf, Hans-Peter ; Kovarik, Jiri ; Heitmann, Daniel ; Koheler, Rolf ; Buch, Tina ; Woisetschlaeger, Maximilian ; Bardroff, Michael Otto ; Patel, Dhavalkumar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CU20190100A73</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>Graf, Christian</creatorcontrib><creatorcontrib>Jostock, Thomas</creatorcontrib><creatorcontrib>Oliver, Stephen John</creatorcontrib><creatorcontrib>Knopf, Hans-Peter</creatorcontrib><creatorcontrib>Kovarik, Jiri</creatorcontrib><creatorcontrib>Heitmann, Daniel</creatorcontrib><creatorcontrib>Koheler, Rolf</creatorcontrib><creatorcontrib>Buch, Tina</creatorcontrib><creatorcontrib>Woisetschlaeger, Maximilian</creatorcontrib><creatorcontrib>Bardroff, Michael Otto</creatorcontrib><creatorcontrib>Patel, Dhavalkumar</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Graf, Christian</au><au>Jostock, Thomas</au><au>Oliver, Stephen John</au><au>Knopf, Hans-Peter</au><au>Kovarik, Jiri</au><au>Heitmann, Daniel</au><au>Koheler, Rolf</au><au>Buch, Tina</au><au>Woisetschlaeger, Maximilian</au><au>Bardroff, Michael Otto</au><au>Patel, Dhavalkumar</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTICUERPOS BIESPECÍFICOS Y MÉTODO DE FABRICACIÓN DE LOS MISMOS</title><date>2020-11-30</date><risdate>2020</risdate><abstract>La invención se refiere a anticuerpos monoclonales biespecíficos bivalentes (bbmAb) o sus variantes, y a métodos de fabricación de dichos anticuerpos mediante la coexpresión de derivados mutados Fc modificados, de dos anticuerpos monoclonales diferentes, en líneas celulares de mamíferos.
The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | spa |
| recordid | cdi_epo_espacenet_CU20190100A7 |
| source | esp@cenet |
| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| title | ANTICUERPOS BIESPECÍFICOS Y MÉTODO DE FABRICACIÓN DE LOS MISMOS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T14%3A53%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Graf,%20Christian&rft.date=2020-11-30&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECU20190100A7%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |