CRYSTALLINE FORM OF A 1-BENZYDRIL-4-ARYL--PIPERAZINDYHYDROCHLORIDE AND PROCESS FOR PREPARING THEREOF

A novel anhydrous crystalline form of 1-benzhydryl-4-allylpiperazine dihydrochloride which possesses absorption bands in its IR-spectra (tablets with nujol mulls) at 646 and 665 cm , a ratio A646/A661 = 0.6, a specific triplet at 915, 926 and 952 cm , a ratio A926/A952 = 0.8, absence of a band at 33...

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Hauptverfasser:	KARAKOLEV PAVEL V.,BG, VITKOVA SNEZANA G.,BG, ZIKOLOVA TATJANA S.,BG, NINOV KIRIL A.,BG, MICEV GEORGI K.,BG, JEVSTATJEVA ANKA B.,BG, NIKOLOV RUMEN K.,BG
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	KARAKOLEV PAVEL V.,BG VITKOVA SNEZANA G.,BG ZIKOLOVA TATJANA S.,BG NINOV KIRIL A.,BG MICEV GEORGI K.,BG JEVSTATJEVA ANKA B.,BG NIKOLOV RUMEN K.,BG
description	A novel anhydrous crystalline form of 1-benzhydryl-4-allylpiperazine dihydrochloride which possesses absorption bands in its IR-spectra (tablets with nujol mulls) at 646 and 665 cm , a ratio A646/A661 = 0.6, a specific triplet at 915, 926 and 952 cm , a ratio A926/A952 = 0.8, absence of a band at 3380 cm and a strongest X-ray diffraction band at 27.4 2 theta , corresponding to 37.8 nm and good water solubility properties rendering it suitable for use in preparation for sterile injectable solutions is prepared by acidifying solutions of 1-benzhydryl-4-allylpiperazine in aqueous alcoholic media.
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	CRYSTALLINE FORM OF A 1-BENZYDRIL-4-ARYL--PIPERAZINDYHYDROCHLORIDE AND PROCESS FOR PREPARING THEREOF
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