DIKETENE IMINE DERIVATIVE AND PROCESS FOR PREPARING THEREOF

DIKETENE IMINE DERIVATIVE AND PROCESS FOR PREPARING THEREOF

The invention relates to the novel compound of formula (I), chemically 1-{2-[(5-N,N-dimethylaminomethyl-2-furyl)-methylthio]ethyl}-2-{2-[(5-N ,N-dimethylaminomethyl-2-furyl)-methylthio]-1-ethylamino} -3-nitro-4-nitromethylene-2-azetine, which is a useful key intermediate in the synthesis of 1-{2-[(5...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HAVASI GABOR, LOSONCZI BELA, GODO LASZLO, KALVIN PETER, HERMANN LASZLO, STEFKO BELA, MEGYERI GABOR, BENCZIK TAMAS, STEFAN LASZLO, JESZENSZKI ANDOR, CZEH MARIA
Format: Patent
Sprache:eng
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator HAVASI GABOR
LOSONCZI BELA
GODO LASZLO
KALVIN PETER
HERMANN LASZLO
STEFKO BELA
MEGYERI GABOR
BENCZIK TAMAS
STEFAN LASZLO
JESZENSZKI ANDOR
CZEH MARIA
description The invention relates to the novel compound of formula (I), chemically 1-{2-[(5-N,N-dimethylaminomethyl-2-furyl)-methylthio]ethyl}-2-{2-[(5-N ,N-dimethylaminomethyl-2-furyl)-methylthio]-1-ethylamino} -3-nitro-4-nitromethylene-2-azetine, which is a useful key intermediate in the synthesis of 1-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethyl}-amino-1-methyla mino-2-nitroethylene (generic name: ranitidine), a known H-2 receptor antagonist. The invention further relates to a process for the preparation of the compound of formula (I), which can be carried out in one simple process step on industrial scale, too. The compound of formula (I) can easily be transformed to ranitidine in one simple step.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CS340291A3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CS340291A3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CS340291A33</originalsourceid><addsrcrecordid>eNrjZLB28fR2DXH1c1Xw9PUEki6uQZ5hjiGeYa4Kjn4uCgFB_s6uwcEKbv5BQLZrgGOQp5-7QoiHa5CrvxsPA2taYk5xKi-U5maQd3MNcfbQTS3Ij08tLkhMTs1LLYl3DjY2MTCyNHQ0NiasAgA4nihw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>DIKETENE IMINE DERIVATIVE AND PROCESS FOR PREPARING THEREOF</title><source>esp@cenet</source><creator>HAVASI GABOR ; LOSONCZI BELA ; GODO LASZLO ; KALVIN PETER ; HERMANN LASZLO ; STEFKO BELA ; MEGYERI GABOR ; BENCZIK TAMAS ; STEFAN LASZLO ; JESZENSZKI ANDOR ; CZEH MARIA</creator><creatorcontrib>HAVASI GABOR ; LOSONCZI BELA ; GODO LASZLO ; KALVIN PETER ; HERMANN LASZLO ; STEFKO BELA ; MEGYERI GABOR ; BENCZIK TAMAS ; STEFAN LASZLO ; JESZENSZKI ANDOR ; CZEH MARIA</creatorcontrib><description>The invention relates to the novel compound of formula (I), chemically 1-{2-[(5-N,N-dimethylaminomethyl-2-furyl)-methylthio]ethyl}-2-{2-[(5-N ,N-dimethylaminomethyl-2-furyl)-methylthio]-1-ethylamino} -3-nitro-4-nitromethylene-2-azetine, which is a useful key intermediate in the synthesis of 1-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethyl}-amino-1-methyla mino-2-nitroethylene (generic name: ranitidine), a known H-2 receptor antagonist. The invention further relates to a process for the preparation of the compound of formula (I), which can be carried out in one simple process step on industrial scale, too. The compound of formula (I) can easily be transformed to ranitidine in one simple step.</description><edition>5</edition><language>eng</language><subject>APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>1992</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19920513&amp;DB=EPODOC&amp;CC=CS&amp;NR=340291A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,782,887,25571,76555</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19920513&amp;DB=EPODOC&amp;CC=CS&amp;NR=340291A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HAVASI GABOR</creatorcontrib><creatorcontrib>LOSONCZI BELA</creatorcontrib><creatorcontrib>GODO LASZLO</creatorcontrib><creatorcontrib>KALVIN PETER</creatorcontrib><creatorcontrib>HERMANN LASZLO</creatorcontrib><creatorcontrib>STEFKO BELA</creatorcontrib><creatorcontrib>MEGYERI GABOR</creatorcontrib><creatorcontrib>BENCZIK TAMAS</creatorcontrib><creatorcontrib>STEFAN LASZLO</creatorcontrib><creatorcontrib>JESZENSZKI ANDOR</creatorcontrib><creatorcontrib>CZEH MARIA</creatorcontrib><title>DIKETENE IMINE DERIVATIVE AND PROCESS FOR PREPARING THEREOF</title><description>The invention relates to the novel compound of formula (I), chemically 1-{2-[(5-N,N-dimethylaminomethyl-2-furyl)-methylthio]ethyl}-2-{2-[(5-N ,N-dimethylaminomethyl-2-furyl)-methylthio]-1-ethylamino} -3-nitro-4-nitromethylene-2-azetine, which is a useful key intermediate in the synthesis of 1-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethyl}-amino-1-methyla mino-2-nitroethylene (generic name: ranitidine), a known H-2 receptor antagonist. The invention further relates to a process for the preparation of the compound of formula (I), which can be carried out in one simple process step on industrial scale, too. The compound of formula (I) can easily be transformed to ranitidine in one simple step.</description><subject>APPARATUS THEREFOR</subject><subject>CHEMISTRY</subject><subject>GENERAL METHODS OF ORGANIC CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1992</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB28fR2DXH1c1Xw9PUEki6uQZ5hjiGeYa4Kjn4uCgFB_s6uwcEKbv5BQLZrgGOQp5-7QoiHa5CrvxsPA2taYk5xKi-U5maQd3MNcfbQTS3Ij08tLkhMTs1LLYl3DjY2MTCyNHQ0NiasAgA4nihw</recordid><startdate>19920513</startdate><enddate>19920513</enddate><creator>HAVASI GABOR</creator><creator>LOSONCZI BELA</creator><creator>GODO LASZLO</creator><creator>KALVIN PETER</creator><creator>HERMANN LASZLO</creator><creator>STEFKO BELA</creator><creator>MEGYERI GABOR</creator><creator>BENCZIK TAMAS</creator><creator>STEFAN LASZLO</creator><creator>JESZENSZKI ANDOR</creator><creator>CZEH MARIA</creator><scope>EVB</scope></search><sort><creationdate>19920513</creationdate><title>DIKETENE IMINE DERIVATIVE AND PROCESS FOR PREPARING THEREOF</title><author>HAVASI GABOR ; LOSONCZI BELA ; GODO LASZLO ; KALVIN PETER ; HERMANN LASZLO ; STEFKO BELA ; MEGYERI GABOR ; BENCZIK TAMAS ; STEFAN LASZLO ; JESZENSZKI ANDOR ; CZEH MARIA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CS340291A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1992</creationdate><topic>APPARATUS THEREFOR</topic><topic>CHEMISTRY</topic><topic>GENERAL METHODS OF ORGANIC CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>HAVASI GABOR</creatorcontrib><creatorcontrib>LOSONCZI BELA</creatorcontrib><creatorcontrib>GODO LASZLO</creatorcontrib><creatorcontrib>KALVIN PETER</creatorcontrib><creatorcontrib>HERMANN LASZLO</creatorcontrib><creatorcontrib>STEFKO BELA</creatorcontrib><creatorcontrib>MEGYERI GABOR</creatorcontrib><creatorcontrib>BENCZIK TAMAS</creatorcontrib><creatorcontrib>STEFAN LASZLO</creatorcontrib><creatorcontrib>JESZENSZKI ANDOR</creatorcontrib><creatorcontrib>CZEH MARIA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HAVASI GABOR</au><au>LOSONCZI BELA</au><au>GODO LASZLO</au><au>KALVIN PETER</au><au>HERMANN LASZLO</au><au>STEFKO BELA</au><au>MEGYERI GABOR</au><au>BENCZIK TAMAS</au><au>STEFAN LASZLO</au><au>JESZENSZKI ANDOR</au><au>CZEH MARIA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DIKETENE IMINE DERIVATIVE AND PROCESS FOR PREPARING THEREOF</title><date>1992-05-13</date><risdate>1992</risdate><abstract>The invention relates to the novel compound of formula (I), chemically 1-{2-[(5-N,N-dimethylaminomethyl-2-furyl)-methylthio]ethyl}-2-{2-[(5-N ,N-dimethylaminomethyl-2-furyl)-methylthio]-1-ethylamino} -3-nitro-4-nitromethylene-2-azetine, which is a useful key intermediate in the synthesis of 1-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethyl}-amino-1-methyla mino-2-nitroethylene (generic name: ranitidine), a known H-2 receptor antagonist. The invention further relates to a process for the preparation of the compound of formula (I), which can be carried out in one simple process step on industrial scale, too. The compound of formula (I) can easily be transformed to ranitidine in one simple step.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_CS340291A3
source esp@cenet
subjects APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title DIKETENE IMINE DERIVATIVE AND PROCESS FOR PREPARING THEREOF
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-04T19%3A30%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HAVASI%20GABOR&rft.date=1992-05-13&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECS340291A3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true