PROCESS FOR PREPARING BIS-ESTERS OF METHANE DIOL WITH 6'-ACYLAMINOPENICILLANIC ACID AND PENICILLANIC ACID 1,1-DIOXIDE

Esters of formula (I) and their salts are new R is H or R1; R1 is a carboxylic acyl gp. Intermediates of formula (V) are also new. (I;R=R1) are hydrolysed in vivo to form penicillanic acid, 1,1-dioxide (II) and the corresp. penicillin (III) and (II) acts as a beta-lactamase inhibitor which potentiat...

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1. Verfasser:	BIGHAM ERIC CLEVELAND
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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