PREPARATION OF NOVEL DERIVATIVES OF INDOLQUINOLIZIDINE
The invention relates to new indolo-quinolizidine derivatives of the general formula (I) or salts or optically active isomers thereof, (I) wherein R stands for an alkyl group, and pharmaceutical compositions containing the same, as well as to a process for the preparation thereof. The new compounds...
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| creator | KARPATI EGON DR.,HU KALAUS GYOERGY DR.,HU SZABO LAJOS DR.,HU SZANTAY CSABA DR.,HU SZPORNY LASZLO DR.,HU |
| description | The invention relates to new indolo-quinolizidine derivatives of the general formula (I) or salts or optically active isomers thereof, (I) wherein R stands for an alkyl group, and pharmaceutical compositions containing the same, as well as to a process for the preparation thereof. The new compounds according to the invention possess vasodilatating and hypotensive effects and can be used in the therapy as medicines. The new compounds according to the invention are completely devoid of harmful side-effects The compounds of the general formula (I), or their salts or optically active isomers, respectively, are prepared according to the invention as follows: a compound of the general formula (IV), (IV) wherein R stands for an alkyl group, or a salt thereof is |
| format | Patent |
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The new compounds according to the invention possess vasodilatating and hypotensive effects and can be used in the therapy as medicines. The new compounds according to the invention are completely devoid of harmful side-effects The compounds of the general formula (I), or their salts or optically active isomers, respectively, are prepared according to the invention as follows: a compound of the general formula (IV), (IV) wherein R stands for an alkyl group, or a salt thereof is</description><edition>3</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1984</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19840514&DB=EPODOC&CC=CS&NR=228102B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19840514&DB=EPODOC&CC=CS&NR=228102B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KARPATI EGON DR.,HU</creatorcontrib><creatorcontrib>KALAUS GYOERGY DR.,HU</creatorcontrib><creatorcontrib>SZABO LAJOS DR.,HU</creatorcontrib><creatorcontrib>SZANTAY CSABA DR.,HU</creatorcontrib><creatorcontrib>SZPORNY LASZLO DR.,HU</creatorcontrib><title>PREPARATION OF NOVEL DERIVATIVES OF INDOLQUINOLIZIDINE</title><description>The invention relates to new indolo-quinolizidine derivatives of the general formula (I) or salts or optically active isomers thereof, (I) wherein R stands for an alkyl group, and pharmaceutical compositions containing the same, as well as to a process for the preparation thereof. 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The new compounds according to the invention are completely devoid of harmful side-effects The compounds of the general formula (I), or their salts or optically active isomers, respectively, are prepared according to the invention as follows: a compound of the general formula (IV), (IV) wherein R stands for an alkyl group, or a salt thereof is</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1984</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDALCHINcAxyDPH091Pwd1Pw8w9z9VFwcQ3yDAOKhbkGgwQ9_Vz8fQJDPf38fTyjPF08_Vx5GFjTEnOKU3mhNDeDvJtriLOHbmpBfnxqcUFicmpeakm8c7CRkYWhgZGTkTFhFQClESd6</recordid><startdate>19840514</startdate><enddate>19840514</enddate><creator>KARPATI EGON DR.,HU</creator><creator>KALAUS GYOERGY DR.,HU</creator><creator>SZABO LAJOS DR.,HU</creator><creator>SZANTAY CSABA DR.,HU</creator><creator>SZPORNY LASZLO DR.,HU</creator><scope>EVB</scope></search><sort><creationdate>19840514</creationdate><title>PREPARATION OF NOVEL DERIVATIVES OF INDOLQUINOLIZIDINE</title><author>KARPATI EGON DR.,HU ; KALAUS GYOERGY DR.,HU ; SZABO LAJOS DR.,HU ; SZANTAY CSABA DR.,HU ; SZPORNY LASZLO DR.,HU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CS228102B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1984</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KARPATI EGON DR.,HU</creatorcontrib><creatorcontrib>KALAUS GYOERGY DR.,HU</creatorcontrib><creatorcontrib>SZABO LAJOS DR.,HU</creatorcontrib><creatorcontrib>SZANTAY CSABA DR.,HU</creatorcontrib><creatorcontrib>SZPORNY LASZLO DR.,HU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KARPATI EGON DR.,HU</au><au>KALAUS GYOERGY DR.,HU</au><au>SZABO LAJOS DR.,HU</au><au>SZANTAY CSABA DR.,HU</au><au>SZPORNY LASZLO DR.,HU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PREPARATION OF NOVEL DERIVATIVES OF INDOLQUINOLIZIDINE</title><date>1984-05-14</date><risdate>1984</risdate><abstract>The invention relates to new indolo-quinolizidine derivatives of the general formula (I) or salts or optically active isomers thereof, (I) wherein R stands for an alkyl group, and pharmaceutical compositions containing the same, as well as to a process for the preparation thereof. The new compounds according to the invention possess vasodilatating and hypotensive effects and can be used in the therapy as medicines. The new compounds according to the invention are completely devoid of harmful side-effects The compounds of the general formula (I), or their salts or optically active isomers, respectively, are prepared according to the invention as follows: a compound of the general formula (IV), (IV) wherein R stands for an alkyl group, or a salt thereof is</abstract><edition>3</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PREPARATION OF NOVEL DERIVATIVES OF INDOLQUINOLIZIDINE |
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