1,2,4-OXADIAZOLE DERIVATIVES AS LIVER X RECEPTOR AGONISTS

Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I'), or pharmaceutical composition...

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Hauptverfasser: SMITH, Jeffrey, LINKENS, Kathryn Taylor, SHAW, Duncan, FLYER, Alec Nathanson, HARDY, Declan, MA, Fupeng, LOREN, Jon Christopher, BOSS, Kelly D, FAN, Yi, MOLTENI, Valentina, SOLOVAY, Catherine Fooks, HUANG, Zhihong
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creator SMITH, Jeffrey
LINKENS, Kathryn Taylor
SHAW, Duncan
FLYER, Alec Nathanson
HARDY, Declan
MA, Fupeng
LOREN, Jon Christopher
BOSS, Kelly D
FAN, Yi
MOLTENI, Valentina
SOLOVAY, Catherine Fooks
HUANG, Zhihong
description Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I'), or pharmaceutical composition described herein. Se proporcionan aquí compuestos y composiciones farmacéuticas útiles para el tratamiento de la disfunción de la glándula de Meibomio (MGD), que comprende administrar a un sujeto que lo necesita una cantidad terapéuticamente eficaz de un compuesto de Fórmula (I) o un compuesto de Fórmula (I'), o una composición farmacéutica descripta en la presente memoria.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 1,2,4-OXADIAZOLE DERIVATIVES AS LIVER X RECEPTOR AGONISTS
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