VARIANTS OF CD38 ANTIBODY AND USES THEREOF
Antibody variants comprising one or more mutations in the Fc region, particularly anti-CD38 antibodies comprising a mutation in one or more amino acid residues corresponding to E430, E345 and S440 in a human IgG1 heavy chain, wherein the amino acid residues are numbered according to the EU index. Va...
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| creator | DE GOEIJ, Bart,E,C,G AHMADI, Tahamtan SATIJN, David ANDRINGA, Grietje SCHUURMAN, Janine BEURSKENS, Frank |
| description | Antibody variants comprising one or more mutations in the Fc region, particularly anti-CD38 antibodies comprising a mutation in one or more amino acid residues corresponding to E430, E345 and S440 in a human IgG1 heavy chain, wherein the amino acid residues are numbered according to the EU index.
Variantes de anticuerpo que comprenden una o más mutaciones en la región Fc, en particular anticuerpos anti-CD38 que comprenden una mutación en uno o más residuos de aminoácidos correspondientes a E430, E345 y S440 en una cadena pesada de la IgG1 humana, en donde los residuos de aminoácidos están numerados de acuerdo con el índice EU. |
| format | Patent |
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Variantes de anticuerpo que comprenden una o más mutaciones en la región Fc, en particular anticuerpos anti-CD38 que comprenden una mutación en uno o más residuos de aminoácidos correspondientes a E430, E345 y S440 en una cadena pesada de la IgG1 humana, en donde los residuos de aminoácidos están numerados de acuerdo con el índice EU.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | VARIANTS OF CD38 ANTIBODY AND USES THEREOF |
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