POLIMORFOS DEL PROFARMACO DE 6-N-(L-ALA-L-ALA)-TROVAFLOXACI- NA
UN PROFARMACO DE TROVAFLOXACINA QUE TIENE LA FOR- MULA I, QUE SE SELECCIONA ENTRE SU POLIMORFO PII Y EL MONOHIDRATO PII.M Y EL PSEUDOMORFO PII.PS DEL MISMO Y PROCEDIMIENTOS PARA SU PREPARACION. SE DESCRIBEN EL POLIMORFO PII Y EL MONOHIDRATO PII.M Y PSEUDOMORFO PII.PS DEL MISMO. LA INVENCION SE REFIE...
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| creator | MELDRUM ALLEN DOUGLAS JOHN NORRIS TIMOTHY MCGARRY JAMES JOHN |
| description | UN PROFARMACO DE TROVAFLOXACINA QUE TIENE LA FOR- MULA I, QUE SE SELECCIONA ENTRE SU POLIMORFO PII Y EL MONOHIDRATO PII.M Y EL PSEUDOMORFO PII.PS DEL MISMO Y PROCEDIMIENTOS PARA SU PREPARACION. SE DESCRIBEN EL POLIMORFO PII Y EL MONOHIDRATO PII.M Y PSEUDOMORFO PII.PS DEL MISMO. LA INVENCION SE REFIERE ADEMAS A PROCEDIMIENTOS DE USO, Y A COMPO- SICIONES FARMACEUTICAS QUE COMPRENDEN LOS COMPU- ESTOS DE LA INVENCION PARA EL TRATAMIENTO DE IN- FECCIONES BACTERINAS EN MAMIFEROS. FIGURA 1
PCT No. PCT/IB96/00653 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/08191 PCT Pub. Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound. |
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PCT No. PCT/IB96/00653 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/08191 PCT Pub. Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound.</description><edition>6</edition><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1997</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970709&DB=EPODOC&CC=CO&NR=4480740A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970709&DB=EPODOC&CC=CO&NR=4480740A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MELDRUM ALLEN DOUGLAS JOHN</creatorcontrib><creatorcontrib>NORRIS TIMOTHY</creatorcontrib><creatorcontrib>MCGARRY JAMES JOHN</creatorcontrib><title>POLIMORFOS DEL PROFARMACO DE 6-N-(L-ALA-L-ALA)-TROVAFLOXACI- NA</title><description>UN PROFARMACO DE TROVAFLOXACINA QUE TIENE LA FOR- MULA I, QUE SE SELECCIONA ENTRE SU POLIMORFO PII Y EL MONOHIDRATO PII.M Y EL PSEUDOMORFO PII.PS DEL MISMO Y PROCEDIMIENTOS PARA SU PREPARACION. SE DESCRIBEN EL POLIMORFO PII Y EL MONOHIDRATO PII.M Y PSEUDOMORFO PII.PS DEL MISMO. LA INVENCION SE REFIERE ADEMAS A PROCEDIMIENTOS DE USO, Y A COMPO- SICIONES FARMACEUTICAS QUE COMPRENDEN LOS COMPU- ESTOS DE LA INVENCION PARA EL TRATAMIENTO DE IN- FECCIONES BACTERINAS EN MAMIFEROS. FIGURA 1
PCT No. PCT/IB96/00653 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/08191 PCT Pub. Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1997</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAP8Pfx9PUPcvMPVnBx9VEICPJ3cwzydXT2B3IVzHT9dDV8dB19HHXBpKZuSJB_mKObj3-Eo7OnroKfIw8Da1piTnEqL5TmZlBwcw1x9tBNLciPTy0uSExOzUstiXf2NzGxMDA3MXA0NCZCCQDSKykV</recordid><startdate>19970709</startdate><enddate>19970709</enddate><creator>MELDRUM ALLEN DOUGLAS JOHN</creator><creator>NORRIS TIMOTHY</creator><creator>MCGARRY JAMES JOHN</creator><scope>EVB</scope></search><sort><creationdate>19970709</creationdate><title>POLIMORFOS DEL PROFARMACO DE 6-N-(L-ALA-L-ALA)-TROVAFLOXACI- NA</title><author>MELDRUM ALLEN DOUGLAS JOHN ; NORRIS TIMOTHY ; MCGARRY JAMES JOHN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CO4480740A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>1997</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MELDRUM ALLEN DOUGLAS JOHN</creatorcontrib><creatorcontrib>NORRIS TIMOTHY</creatorcontrib><creatorcontrib>MCGARRY JAMES JOHN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MELDRUM ALLEN DOUGLAS JOHN</au><au>NORRIS TIMOTHY</au><au>MCGARRY JAMES JOHN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>POLIMORFOS DEL PROFARMACO DE 6-N-(L-ALA-L-ALA)-TROVAFLOXACI- NA</title><date>1997-07-09</date><risdate>1997</risdate><abstract>UN PROFARMACO DE TROVAFLOXACINA QUE TIENE LA FOR- MULA I, QUE SE SELECCIONA ENTRE SU POLIMORFO PII Y EL MONOHIDRATO PII.M Y EL PSEUDOMORFO PII.PS DEL MISMO Y PROCEDIMIENTOS PARA SU PREPARACION. SE DESCRIBEN EL POLIMORFO PII Y EL MONOHIDRATO PII.M Y PSEUDOMORFO PII.PS DEL MISMO. LA INVENCION SE REFIERE ADEMAS A PROCEDIMIENTOS DE USO, Y A COMPO- SICIONES FARMACEUTICAS QUE COMPRENDEN LOS COMPU- ESTOS DE LA INVENCION PARA EL TRATAMIENTO DE IN- FECCIONES BACTERINAS EN MAMIFEROS. FIGURA 1
PCT No. PCT/IB96/00653 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/08191 PCT Pub. Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | POLIMORFOS DEL PROFARMACO DE 6-N-(L-ALA-L-ALA)-TROVAFLOXACI- NA |
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