Lípidos catiónicos ionizables y nanopartículas lipídicas, y métodos de síntesis y uso de los mismos
Se proporcionan lípidos catiónicos ionizables y nanopartículas lipídicas para la administración de ácidos nucleicos a células (p. ej., células inmunes), y métodos para preparar y usar dichos lípidos y nanopartículas lipídicas dirigidas. Provided are ionizable cationic lipids and lipid nanoparticles...
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| creator | NIELSEN, Ulrik BOESCH, Austin Wayne ALI, Mir DRUMMOND, Daryl Clark KUHLMAN, William |
| description | Se proporcionan lípidos catiónicos ionizables y nanopartículas lipídicas para la administración de ácidos nucleicos a células (p. ej., células inmunes), y métodos para preparar y usar dichos lípidos y nanopartículas lipídicas dirigidas.
Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., immune cells), and methods of making and using such lipids and targeted lipid nanoparticles. |
| format | Patent |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Lípidos catiónicos ionizables y nanopartículas lipídicas, y métodos de síntesis y uso de los mismos |
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