SAMPLE HOLDER AND SYSTEM INCLUDING THE SAME

A sample holder includes a first member having a first holding mechanism feature, the first holding mechanism configured to hold a first substrate including a sample, a second member having a second holding mechanism feature, the second holding mechanism configured to hold a second substrate including a reagent medium, and an alignment mechanism, and an alignment mechanism coupled to at least one of the first member and the second member and configured to align the first member and the second member such that the sample contacts at least a portion of the reagent medium when the first member and the second member are aligned. 一种样品保持器，包括第一构件、第二构件和对正机构，第一构件具有第一保持机构特征，第一保持机构配置为保持包括样品的第一基板，第二构件具有第二保持机构特，第二保持机构配置为保持包括试剂介质的第二基板，并且对正机构连接到第一构件和第二构件中的至少一者并配置为对正第一构件和第二构件使得当第一构件和第二构件对正时样品接触试剂介质的至少一部分。