Use of estrone derivative EA204 in preparing vascular smooth muscle relaxant

The present invention relates to medicine technology, and is especially the application of estrone derivative EA204 in preparing medicine for treating vascular smooth muscle spasm disease. In in vitro animal experiment, estrone derivative EA204 can relax rabbit's in vitro descending aorta contr...

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creator SHOUTING,LI FU
description The present invention relates to medicine technology, and is especially the application of estrone derivative EA204 in preparing medicine for treating vascular smooth muscle spasm disease. In in vitro animal experiment, estrone derivative EA204 can relax rabbit's in vitro descending aorta contracted with adrenalin, noradrenalin, barium chloride or potassium chloride. Estrone derivative EA204 may be used in preparing medicine for treating hypertension, coronary atherosclerosis, cerebral vascular spasm disease, etc.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Use of estrone derivative EA204 in preparing vascular smooth muscle relaxant
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