Thieno[3,2-b]pyridine-6-carbonitriles as protein kinase inhibitors

Thieno[3,2-b]pyridine-6-carbonitriles as protein kinase inhibitors

This invention provides compounds of Formula (1a)-(1f), II wherein: X, m, n, q, R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Q, Z, Z', Z''', Z'' and J are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, ne...

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1. Verfasser: BOSCHELLI DIANE HARRIS,ZHANG NAN,BARRIOS SOSA ANACAROLINA,DURUTLIC HARIS,WU BIQI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:This invention provides compounds of Formula (1a)-(1f), II wherein: X, m, n, q, R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Q, Z, Z', Z''', Z'' and J are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, neuropathic pain, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.