Anti-P-selectin antibodies

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suff...

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1. Verfasser: GRAUS YVO,HIMBER JACQUES,JANSEN-MOLENAAR MIRANDA,KLING DOROTHEE,KOPETZKY ERHARD,PARREN PAUL,REBERS FRANK,STEINER BEAT,STERN ANNE,STREIN PAMELA,STUBENRAUCH KAY-GUNNAR,VAN DE WINKEL JAN,VAN VUGT MARTINE
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creator GRAUS YVO,HIMBER JACQUES,JANSEN-MOLENAAR MIRANDA,KLING DOROTHEE,KOPETZKY ERHARD,PARREN PAUL,REBERS FRANK,STEINER BEAT,STERN ANNE,STREIN PAMELA,STUBENRAUCH KAY-GUNNAR,VAN DE WINKEL JAN,VAN VUGT MARTINE
description This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Anti-P-selectin antibodies
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