Niosame having metal porphyrin complex embedded therein, process for it and drug with use thereof

A niosome having a metal porphyrin complex embedded therein which contains a cationized metal porphyrin complex and a niosome-forming substance. This niosome having a metal porphyrin complex embedded therein has an SOD activity and can target super oxide anion radical (O2) and surely decrease it. Be...

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1. Verfasser: YUASA MAKATO,OYAIZU KENICHI,YAMAGUCHI ARITOMO,HANYUU YUKIHIKO,KASAHARA KAZUNORI,KOMURO MASAYASU
Format: Patent
Sprache:eng
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Zusammenfassung:A niosome having a metal porphyrin complex embedded therein which contains a cationized metal porphyrin complex and a niosome-forming substance. This niosome having a metal porphyrin complex embedded therein has an SOD activity and can target super oxide anion radical (O2) and surely decrease it. Because of being in the form of a niosome, it can be delivered to, for example, a cancer cell in vivo. Therefore, it can decrease O2 in a cancer cell and exert an excellent effect of treating cancer. Moreover, it shows a selective effect and, therefore, is usable as a novel anticancer agent with no side effect. In addition, it can be hold in the blood, which makes it favorable as an antioxidant. Owing to this characteristic, it can protect the living body from in vivo disorders caused by active oxygen.