Indanol derivative

The present invention provides a compound having the following general formula (I) which is useful as a neurokinin receptor antagonist: (wherein, R 1 , R 2 : optionally substituted (hetero)aryl, R 3 : -CO-R 4 , -CO-O-R 4 , etc., R 4 : alkyl, cycloalkyl, etc., A: CH 2 , CO, SO 2 , B: a single bond, e...

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1. Verfasser: NISHI TAKEHIDE,TAKEMOTO TOSHIYASU,MORIMOTO KIYOSHI,IKEDA TAKUYA
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creator NISHI TAKEHIDE,TAKEMOTO TOSHIYASU,MORIMOTO KIYOSHI,IKEDA TAKUYA
description The present invention provides a compound having the following general formula (I) which is useful as a neurokinin receptor antagonist: (wherein, R 1 , R 2 : optionally substituted (hetero)aryl, R 3 : -CO-R 4 , -CO-O-R 4 , etc., R 4 : alkyl, cycloalkyl, etc., A: CH 2 , CO, SO 2 , B: a single bond, etc., D: oxygen, CH 2 , E: alkylene, alkenylene, n: 1 to 3).
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Indanol derivative
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