Novel farnesyl protein transferase inhibitors as antitumor agents

Disclosed are novel tricyclic compounds of the formula (I) and a pharmaceutically acceptable salts or solvates thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising the compounds of formula (I). Also disclosed are use...

Ausführliche Beschreibung

Bibliographische Detailangaben

1. Verfasser:	ZHU HUGH Y.,COOPER ALAN B.,DESAI JAGDISH A.,WANG JAMES J-S,RANE DINANATH F.,DOLL RONALD J.,NJOROGE F. GEORGE,GIRIJAVALLABHAN VIYYOOR M
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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