D-calcium pantothenate synthesis method

The invention discloses a synthesis method for D-calcium pantothenate, which comprises: synthesizing keto lactone pantothenate with diethyl oxalate, isobutanal and formaldehyde, reducing said product, using carbamidine carbonate to resolution out D-pantothenic carbonate and L- pantothenic carbonate;...

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1. Verfasser: TIANXING,LUO WU
Format: Patent
Sprache:eng
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Zusammenfassung:The invention discloses a synthesis method for D-calcium pantothenate, which comprises: synthesizing keto lactone pantothenate with diethyl oxalate, isobutanal and formaldehyde, reducing said product, using carbamidine carbonate to resolution out D-pantothenic carbonate and L- pantothenic carbonate; preparing the product with D-pantoic lactone, beta-alanine both from D-pantothenic carbonate and calcium metal. This invention avoids the application of hypertoxic sodium cyanide, stabilizes product quality, and increases material utilization ratio.