Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate

The present invention provides a process for the preparation of 4-methyl-5-formyl-thiazole of the formula (I)which comprises reducing the thiazole ester of the formula (III) to thiazole alcohol of the formula (IV), using sodium borohydride in the presence of AlCl3 in a solvent and oxidising using an...

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1. Verfasser: DESHPANDE PANDURANG BALWANT,LUTHRA PARVEN KUMAR,VYAS RAJESH,KAMMA RAMAKRISHNA
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creator DESHPANDE PANDURANG BALWANT,LUTHRA PARVEN KUMAR,VYAS RAJESH,KAMMA RAMAKRISHNA
description The present invention provides a process for the preparation of 4-methyl-5-formyl-thiazole of the formula (I)which comprises reducing the thiazole ester of the formula (III) to thiazole alcohol of the formula (IV), using sodium borohydride in the presence of AlCl3 in a solvent and oxidising using an oxidizing agent the thiazole alcohol of the formula (IV) to obtain 4-methyl-5-formyl-thiazole of the formula (I).
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subjects APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate
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