Method for preparing benzenesulfonyl compounds

Method for preparing benzenesulfonyl compounds

The present disclosure provides a method for the preparation of aromatic sulfonyl halides by contacting a substituted phenyl compound with a halosulfonic acid and trifluoroacetic acid. The present disclosure further provides a method for the preparation of 4-[5-methyl-3-phenylisoxazol-4-yl]benzenesu...

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Hauptverfasser: KUNDA SASTRY A, GALLAGHER DONALD J, LETENDRE LEO J, MCLAUGHLIN KATHLEEN, SEANEY LISA M
Format: Patent
Sprache:eng
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator KUNDA SASTRY A
GALLAGHER DONALD J
LETENDRE LEO J
MCLAUGHLIN KATHLEEN
SEANEY LISA M
description The present disclosure provides a method for the preparation of aromatic sulfonyl halides by contacting a substituted phenyl compound with a halosulfonic acid and trifluoroacetic acid. The present disclosure further provides a method for the preparation of 4-[5-methyl-3-phenylisoxazol-4-yl]benzenesulfonamide which is useful in treating cyclooxygenase-2 related disorders.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Method for preparing benzenesulfonyl compounds
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