New use of qingkailing preparation in treating of acute anhelation syndrome
A new application of medicine "Qingkailing" in treating acute respiratory distress syndrome (ARDS) is disclosed. 本发明公开清开灵中药制剂应用于变异冠状病毒引起的非典型性肺炎等肺严重损害性疾病发生ARDS时的新用途。利用油酸所致家兔ARDS模型的肺毛细血管损伤肺微循环障碍、血管内皮细胞及肺泡上皮损伤通透性增加，导致间质水肿、出血等病理改变及肺泡表面活性物质的破坏，模拟非典型肺炎的病理形态及病理生理的改变。清开灵注射液显示能减轻拟ARDS的肺泡与间质渗出，提高了肺脏...
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| creator | PENGTAO LI XU JIA YANSHU PAN |
| description | A new application of medicine "Qingkailing" in treating acute respiratory distress syndrome (ARDS) is disclosed.
本发明公开清开灵中药制剂应用于变异冠状病毒引起的非典型性肺炎等肺严重损害性疾病发生ARDS时的新用途。利用油酸所致家兔ARDS模型的肺毛细血管损伤肺微循环障碍、血管内皮细胞及肺泡上皮损伤通透性增加，导致间质水肿、出血等病理改变及肺泡表面活性物质的破坏，模拟非典型肺炎的病理形态及病理生理的改变。清开灵注射液显示能减轻拟ARDS的肺泡与间质渗出，提高了肺脏的气体弥散交换能力，改善低血氧分压状态，并显著提高血氧饱和度，从而发挥抗ARDS的作用。 |
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本发明公开清开灵中药制剂应用于变异冠状病毒引起的非典型性肺炎等肺严重损害性疾病发生ARDS时的新用途。利用油酸所致家兔ARDS模型的肺毛细血管损伤肺微循环障碍、血管内皮细胞及肺泡上皮损伤通透性增加，导致间质水肿、出血等病理改变及肺泡表面活性物质的破坏，模拟非典型肺炎的病理形态及病理生理的改变。清开灵注射液显示能减轻拟ARDS的肺泡与间质渗出，提高了肺脏的气体弥散交换能力，改善低血氧分压状态，并显著提高血氧饱和度，从而发挥抗ARDS的作用。</description><edition>7</edition><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040218&DB=EPODOC&CC=CN&NR=1475264A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040218&DB=EPODOC&CC=CN&NR=1475264A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PENGTAO LI</creatorcontrib><creatorcontrib>XU JIA</creatorcontrib><creatorcontrib>YANSHU PAN</creatorcontrib><title>New use of qingkailing preparation in treating of acute anhelation syndrome</title><description>A new application of medicine "Qingkailing" in treating acute respiratory distress syndrome (ARDS) is disclosed.
本发明公开清开灵中药制剂应用于变异冠状病毒引起的非典型性肺炎等肺严重损害性疾病发生ARDS时的新用途。利用油酸所致家兔ARDS模型的肺毛细血管损伤肺微循环障碍、血管内皮细胞及肺泡上皮损伤通透性增加，导致间质水肿、出血等病理改变及肺泡表面活性物质的破坏，模拟非典型肺炎的病理形态及病理生理的改变。清开灵注射液显示能减轻拟ARDS的肺泡与间质渗出，提高了肺脏的气体弥散交换能力，改善低血氧分压状态，并显著提高血氧饱和度，从而发挥抗ARDS的作用。</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPD2Sy1XKC1OVchPUyjMzEvPTszMAVIKBUWpBYlFiSWZ-XkKmXkKJUWpQDZQHKgsMbm0JFUhMS8jNQciX1yZl1KUn5vKw8CalphTnMoLpbkZ5N1cQ5w9dFML8uNTiwsSk1PzUkvinf0MTcxNjcxMHI0JqwAAmcw01w</recordid><startdate>20040218</startdate><enddate>20040218</enddate><creator>PENGTAO LI</creator><creator>XU JIA</creator><creator>YANSHU PAN</creator><scope>EVB</scope></search><sort><creationdate>20040218</creationdate><title>New use of qingkailing preparation in treating of acute anhelation syndrome</title><author>PENGTAO LI ; XU JIA ; YANSHU PAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN1475264A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2004</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PENGTAO LI</creatorcontrib><creatorcontrib>XU JIA</creatorcontrib><creatorcontrib>YANSHU PAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PENGTAO LI</au><au>XU JIA</au><au>YANSHU PAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>New use of qingkailing preparation in treating of acute anhelation syndrome</title><date>2004-02-18</date><risdate>2004</risdate><abstract>A new application of medicine "Qingkailing" in treating acute respiratory distress syndrome (ARDS) is disclosed.
本发明公开清开灵中药制剂应用于变异冠状病毒引起的非典型性肺炎等肺严重损害性疾病发生ARDS时的新用途。利用油酸所致家兔ARDS模型的肺毛细血管损伤肺微循环障碍、血管内皮细胞及肺泡上皮损伤通透性增加，导致间质水肿、出血等病理改变及肺泡表面活性物质的破坏，模拟非典型肺炎的病理形态及病理生理的改变。清开灵注射液显示能减轻拟ARDS的肺泡与间质渗出，提高了肺脏的气体弥散交换能力，改善低血氧分压状态，并显著提高血氧饱和度，从而发挥抗ARDS的作用。</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| title | New use of qingkailing preparation in treating of acute anhelation syndrome |
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