Drug releasing biodegradable fiber implant

The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal dis...

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Hauptverfasser: WAGGONER PAULA, SMITH GEORGE M, ROMERO-SANCHEZ ANDRES A, ALIKACEM NADIR, RADULESCU DELIA, HU ZHIBING, NELSON KEVIN D
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creator WAGGONER PAULA
SMITH GEORGE M
ROMERO-SANCHEZ ANDRES A
ALIKACEM NADIR
RADULESCU DELIA
HU ZHIBING
NELSON KEVIN D
description The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.
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subjects APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBONFILAMENTS
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS,THREADS, FIBRES, BRISTLES OR RIBBONS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
HUMAN NECESSITIES
HYGIENE
LAUNDERING
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
NATURAL OR ARTIFICIAL THREADS OR FIBRES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPINNING
TEXTILES
TREATMENT OF TEXTILES OR THE LIKE
TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS,FABRICS, FEATHERS, OR FIBROUS GOODS MADE FROM SUCH MATERIALS
title Drug releasing biodegradable fiber implant
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