Use of ATase inhibitor in preparing synergistic pharmaceutical composition for human cancer cell toxicity

The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O -benzylguanine.

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1. Verfasser: JOHN COLIN BAER,AZADEH ALISON FREEMAN,EDWARD STUART NEWLANDS
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creator JOHN COLIN BAER,AZADEH ALISON FREEMAN,EDWARD STUART NEWLANDS
description The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O -benzylguanine.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Use of ATase inhibitor in preparing synergistic pharmaceutical composition for human cancer cell toxicity
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