Amino acid ester containing azole antifungal agent

The present invention concerns novel compounds of formulathe N-oxide forms, the pharmaceutically acceptable addition salts thereof and stereochemically isomeric forms thereof, wherein -A-B- forms a bivalent radical of formula -N=CH- (a), -CH=N- (b), -CH=CH- (c), L represents the acyl moiety of an am...

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1. Verfasser: L. MEERPOEL,J. HEERES,R. J. M. HENDRICKX
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creator L. MEERPOEL,J. HEERES,R. J. M. HENDRICKX
description The present invention concerns novel compounds of formulathe N-oxide forms, the pharmaceutically acceptable addition salts thereof and stereochemically isomeric forms thereof, wherein -A-B- forms a bivalent radical of formula -N=CH- (a), -CH=N- (b), -CH=CH- (c), L represents the acyl moiety of an amino acid; D is an azole containing 1,3- or 1,4-dioxolane derivative as broad-spectrum antifungals; their preparation, compositions containing them and their use as a medicine.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Amino acid ester containing azole antifungal agent
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