Monoclonal antibody aiming at triiodothyronine, detection reagent based on monoclonal antibody and application of monoclonal antibody
The invention relates to a monoclonal antibody aiming at triiodothyronine (T3) or an antigen binding fragment thereof, a related nucleic acid product, a cell product, a detection reagent or a kit as well as a preparation method and application thereof. The monoclonal antibody or the antigen binding...
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| creator | DAI ZHAN TAO YANMENG LIN FEI DONG WANCHUN LI HAICHENG GAO GE |
| description | The invention relates to a monoclonal antibody aiming at triiodothyronine (T3) or an antigen binding fragment thereof, a related nucleic acid product, a cell product, a detection reagent or a kit as well as a preparation method and application thereof. The monoclonal antibody or the antigen binding fragment of the monoclonal antibody can be bound with T3 with high specificity and high affinity, so that the detection accuracy and sensitivity of the T3 are improved; moreover, the invention also develops a high-performance pairing antibody suitable for double-antibody sandwich method immunodetection, thereby breaking through the limitation of low sensitivity and poor clinical correlation of a traditional competition method detection reagent, and realizing double-antibody sandwich method immunodetection of T3. The antibody has important significance on early diagnosis and treatment of thyroid diseases and domestic replacement of core antibody raw materials.
本发明涉及针对三碘甲状腺原氨酸(T3)的单克隆抗体或其抗原结合片段，其相关核酸产品、细胞产品、检测试剂或试剂盒及 |
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本发明涉及针对三碘甲状腺原氨酸(T3)的单克隆抗体或其抗原结合片段，其相关核酸产品、细胞产品、检测试剂或试剂盒及</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240924&DB=EPODOC&CC=CN&NR=118684770A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240924&DB=EPODOC&CC=CN&NR=118684770A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DAI ZHAN</creatorcontrib><creatorcontrib>TAO YANMENG</creatorcontrib><creatorcontrib>LIN FEI</creatorcontrib><creatorcontrib>DONG WANCHUN</creatorcontrib><creatorcontrib>LI HAICHENG</creatorcontrib><creatorcontrib>GAO GE</creatorcontrib><title>Monoclonal antibody aiming at triiodothyronine, detection reagent based on monoclonal antibody and application of monoclonal antibody</title><description>The invention relates to a monoclonal antibody aiming at triiodothyronine (T3) or an antigen binding fragment thereof, a related nucleic acid product, a cell product, a detection reagent or a kit as well as a preparation method and application thereof. The monoclonal antibody or the antigen binding fragment of the monoclonal antibody can be bound with T3 with high specificity and high affinity, so that the detection accuracy and sensitivity of the T3 are improved; moreover, the invention also develops a high-performance pairing antibody suitable for double-antibody sandwich method immunodetection, thereby breaking through the limitation of low sensitivity and poor clinical correlation of a traditional competition method detection reagent, and realizing double-antibody sandwich method immunodetection of T3. The antibody has important significance on early diagnosis and treatment of thyroid diseases and domestic replacement of core antibody raw materials.
本发明涉及针对三碘甲状腺原氨酸(T3)的单克隆抗体或其抗原结合片段，其相关核酸产品、细胞产品、检测试剂或试剂盒及</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKwkAQRdNYiHqHsVcwKCatBMVGK_sw2Z3Egc3MspkmB_DeilimsHrwef_Ns9dNRV1QwQAoxo36EZB7lg7QwBKzerXnmFRYaAOejJyxCiTCjsSgwYE8fIZ-KiUeMMbADr8nbae0ZTZrMQy0-nGRrS_nR3XdUtSahoiOhKyu7nleHstDUexO-3-cN4eFTFE</recordid><startdate>20240924</startdate><enddate>20240924</enddate><creator>DAI ZHAN</creator><creator>TAO YANMENG</creator><creator>LIN FEI</creator><creator>DONG WANCHUN</creator><creator>LI HAICHENG</creator><creator>GAO GE</creator><scope>EVB</scope></search><sort><creationdate>20240924</creationdate><title>Monoclonal antibody aiming at triiodothyronine, detection reagent based on monoclonal antibody and application of monoclonal antibody</title><author>DAI ZHAN ; TAO YANMENG ; LIN FEI ; DONG WANCHUN ; LI HAICHENG ; GAO GE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN118684770A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>DAI ZHAN</creatorcontrib><creatorcontrib>TAO YANMENG</creatorcontrib><creatorcontrib>LIN FEI</creatorcontrib><creatorcontrib>DONG WANCHUN</creatorcontrib><creatorcontrib>LI HAICHENG</creatorcontrib><creatorcontrib>GAO GE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DAI ZHAN</au><au>TAO YANMENG</au><au>LIN FEI</au><au>DONG WANCHUN</au><au>LI HAICHENG</au><au>GAO GE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Monoclonal antibody aiming at triiodothyronine, detection reagent based on monoclonal antibody and application of monoclonal antibody</title><date>2024-09-24</date><risdate>2024</risdate><abstract>The invention relates to a monoclonal antibody aiming at triiodothyronine (T3) or an antigen binding fragment thereof, a related nucleic acid product, a cell product, a detection reagent or a kit as well as a preparation method and application thereof. The monoclonal antibody or the antigen binding fragment of the monoclonal antibody can be bound with T3 with high specificity and high affinity, so that the detection accuracy and sensitivity of the T3 are improved; moreover, the invention also develops a high-performance pairing antibody suitable for double-antibody sandwich method immunodetection, thereby breaking through the limitation of low sensitivity and poor clinical correlation of a traditional competition method detection reagent, and realizing double-antibody sandwich method immunodetection of T3. The antibody has important significance on early diagnosis and treatment of thyroid diseases and domestic replacement of core antibody raw materials.
本发明涉及针对三碘甲状腺原氨酸(T3)的单克隆抗体或其抗原结合片段，其相关核酸产品、细胞产品、检测试剂或试剂盒及</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE |
| title | Monoclonal antibody aiming at triiodothyronine, detection reagent based on monoclonal antibody and application of monoclonal antibody |
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