Compounds for treatment of fascioliasis

The invention relates to a compound for treating fluke flakes, in particular to a compound of formula (1b), (1c), (1d) or (1e) for treating or preventing fluke flakes, and pharmaceutically acceptable salts or solvates of the compound of formula (1b), (1c), (1d) or (1e). Some of these compounds themselves are novel compounds and also have activity as schistosome growth inhibitors. The invention also relates to pharmaceutical compositions comprising such novel compounds, salts or solvates, and to the use of such novel compounds as medicaments, in particular in the treatment or prevention of schistosomiasis, also referred to as schistosomiasis. # imgabs0 # 本发明涉及用于治疗片形吸虫病的化合物，具体涉及治疗或预防片形吸虫病的式(1b)、(1c)、(1d)或(1e)的化合物及其药学上可接受的盐或溶剂合物。这些化合物中的一些本身是新型化合物，并且还具有作为血吸虫生长抑制剂的活性。本发明还涉及包含此类新型化合物、盐或溶剂合物的药物组合物，并且涉及此类新型化合物作为药物的用途，特别是在治疗或预防也称为裂体吸虫病的血吸虫病方面的用途。#imgabs0#