Method for shortening fermentation period of tylosin

The invention relates to the technical field of microbial fermentation, in particular to a method for shortening the fermentation period of tylosin. According to the method, a four-stage fermentation mode is adopted, and by prolonging the culture period of a seed tank, improving the culture temperat...

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Bibliographische Detailangaben
Hauptverfasser: LI XUZHOU, HAN JIE, GUO ZHONG, FU JIAHAO, DAI JUN, XU JIYUN, LANG KEPENG, WU HAO, YU CHEN, LIU YANGFAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of microbial fermentation, in particular to a method for shortening the fermentation period of tylosin. According to the method, a four-stage fermentation mode is adopted, and by prolonging the culture period of a seed tank, improving the culture temperature of the seed tank, increasing the use amount of carbon sources and nitrogen sources of the seed tank, reducing the delayed nitrogen source proportion of the fermentation tank, improving the quick-acting nitrogen source proportion, improving the initial culture temperature of the fermentation tank and increasing the digested volume of the fermentation tank, the yield is increased; and in the fermentation process, the fermentation volume is rapidly increased by supplementing water, so that the tylosin product inhibition effect is reduced. By adopting the process disclosed by the invention, the fermentation period can be greatly shortened, the component D can be controlled within 2.5% on the premise of not changing