Engineered halomonas for producing PHA (polyhydroxyalkanoate) and PHA production method
The invention relates to the technical field of microorganisms, in particular to an engineered halomonas for producing PHA and a production method of the PHA. It is found that the requirement of halomonas on dissolved oxygen in the later stage of fermentation can be remarkably reduced by reducing th...
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| creator | LIU WEI ZHANG LIZHAN |
| description | The invention relates to the technical field of microorganisms, in particular to an engineered halomonas for producing PHA and a production method of the PHA. It is found that the requirement of halomonas on dissolved oxygen in the later stage of fermentation can be remarkably reduced by reducing the expression quantity of the cytochrome d oxidase compound gene cydA or the activity of the encoded protein of the cytochrome d oxidase compound gene cydA, the purpose that the strain can still efficiently conduct PHA synthesis under the low-rotation-speed even stirring-free anoxic or anaerobic condition in the later stage of fermentation is achieved, and then the yield of PHA is effectively increased. According to the engineering halomonas provided by the invention, the yield of PHA is remarkably increased under the low-rotating-speed even stirring-free anoxic or anaerobic condition in the later stage of fermentation, the energy consumption in the fermentation process is reduced, and an effective solution is provi |
| format | Patent |
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It is found that the requirement of halomonas on dissolved oxygen in the later stage of fermentation can be remarkably reduced by reducing the expression quantity of the cytochrome d oxidase compound gene cydA or the activity of the encoded protein of the cytochrome d oxidase compound gene cydA, the purpose that the strain can still efficiently conduct PHA synthesis under the low-rotation-speed even stirring-free anoxic or anaerobic condition in the later stage of fermentation is achieved, and then the yield of PHA is effectively increased. 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It is found that the requirement of halomonas on dissolved oxygen in the later stage of fermentation can be remarkably reduced by reducing the expression quantity of the cytochrome d oxidase compound gene cydA or the activity of the encoded protein of the cytochrome d oxidase compound gene cydA, the purpose that the strain can still efficiently conduct PHA synthesis under the low-rotation-speed even stirring-free anoxic or anaerobic condition in the later stage of fermentation is achieved, and then the yield of PHA is effectively increased. 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It is found that the requirement of halomonas on dissolved oxygen in the later stage of fermentation can be remarkably reduced by reducing the expression quantity of the cytochrome d oxidase compound gene cydA or the activity of the encoded protein of the cytochrome d oxidase compound gene cydA, the purpose that the strain can still efficiently conduct PHA synthesis under the low-rotation-speed even stirring-free anoxic or anaerobic condition in the later stage of fermentation is achieved, and then the yield of PHA is effectively increased. According to the engineering halomonas provided by the invention, the yield of PHA is remarkably increased under the low-rotating-speed even stirring-free anoxic or anaerobic condition in the later stage of fermentation, the energy consumption in the fermentation process is reduced, and an effective solution is provi</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Engineered halomonas for producing PHA (polyhydroxyalkanoate) and PHA production method |
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