Combination of budesonide and 5-amino-2, 3-dihydro-1, 4-phthalazindione

The present invention relates to a combination of budesonide and a 5-amino-2, 3-dihydro-1, 4-phthalazindione or one of the pharmaceutically acceptable salts thereof. The pharmaceutical composition is used for treating chronic inflammatory diseases, especially CORD, asthma, Crohn's disease, ulcerative colitis and autoimmune hepatitis. In particular, the invention relates to the use of a sodium salt of 5-amino-2, 3-dihydro-1, 4-phthalazindione in such a combination. Pharmaceutical compositions, advantageous techniques of formulation, and methods of treatment are disclosed. 本发明涉及布地奈德与5-氨基-2,3-二氢-1,4-酞嗪二酮或其药学上可接受的盐之一的组合。该药物组合应用于治疗慢性炎性疾病，尤其是CORD、哮喘、克罗恩氏病、溃疡性结肠炎和自身免疫性肝炎。本发明特别涉及5-氨基-2,3-二氢-1,4-酞嗪二酮钠盐在该组合中的用途。公开了药物组合物、有利的制剂技术和治疗方法。