Purification method of pyrrolotriazine compound or derivative thereof

The invention relates to a method for purifying a pyrrolotriazine compound or a derivative thereof, and belongs to the field of purification of medical intermediates, and the method comprises the following steps: thermally dissolving a crude product of the pyrrolotriazine compound obtained by preliminary purification in an organic solvent 1, then dropwise adding a proper alkali aqueous solution into the crude product, and crystallizing to obtain the pyrrolotriazine compound or the derivative thereof. According to the method disclosed by the invention, the pyrrolotriazine compound is purified by adopting a crystallization process, and the method has the advantages of simplicity in operation and strong purification capacity. 本发明涉及一种吡咯并三嗪类化合物或其衍生物的纯化方法，属于医药中间体纯化领域，该方法将初步纯化得到吡咯并三嗪类化合物的粗品热溶于有机溶剂1，然后选择合适的碱的水溶液滴加入粗品中进行结晶，再降温过滤干燥得到纯度较高的吡咯并三嗪类化合物，该方法采用结晶工艺提纯吡咯并三嗪类化合物，具有操作简单，纯化能力强的优点。