Application of compound CR-5884 in preparation of ovarian cancer stem cell proliferation inhibitor

Application of compound CR-5884 in preparation of ovarian cancer stem cell proliferation inhibitor

The invention discloses an application of a compound CR-5884 in preparation of an ovarian cancer stem cell proliferation inhibitor. Cell experiments and in-vivo experiments prove that the compound CBR-5884 can effectively inhibit proliferation of ovarian cancer stem cells, so that subcutaneous growt...

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Hauptverfasser: XIE XIAOHUI, FANG TIANLIN, CHEN MIAOJUAN, YANG XUEFEN, ZHENG YANQIN, GONG KUNXIANG, SU MINTING, SHI KUN
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator XIE XIAOHUI
FANG TIANLIN
CHEN MIAOJUAN
YANG XUEFEN
ZHENG YANQIN
GONG KUNXIANG
SU MINTING
SHI KUN
description The invention discloses an application of a compound CR-5884 in preparation of an ovarian cancer stem cell proliferation inhibitor. Cell experiments and in-vivo experiments prove that the compound CBR-5884 can effectively inhibit proliferation of ovarian cancer stem cells, so that subcutaneous growth of ovarian tumors is reduced, a new method is provided for inhibiting the ovarian cancer stem cells, and the compound CBR-5884 is expected to be applied to preparation of reagents for inhibiting proliferation of the ovarian cancer stem cells. It is proved for the first time that the compound CBR-5884 can effectively inhibit ovarian cancer stem cells, a new thought is provided for clinical treatment of ovarian cancer, and the compound CBR-5884 has important potential application value. 本发明公开了化合物CBR-5884在制备卵巢癌干细胞增殖抑制剂中的应用。本发明通过细胞实验和体内实验证实，化合物CBR-5884可有效抑制卵巢癌干细胞的增殖，从而减少卵巢肿瘤在皮下的生长，为抑制卵巢癌干细胞提供了新的方法，有望应用于制备抑制卵巢癌干细胞增殖的试剂。本发明首次证明化合物CBR-5884可有效抑制卵巢癌干细胞，给卵巢癌临床治疗提供了新的思路，具有重要的潜在应用价值。
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Application of compound CR-5884 in preparation of ovarian cancer stem cell proliferation inhibitor
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