Synthesis method and application of agrimonol F
The invention discloses a synthesis method and application of hairyvein agrimony phenol F. The structure of the hairyvein agrimony phenol F is as shown in a formula (V), and the synthesis method is characterized in that a preparation method of a compound as shown in a formula (I) is carried out acco...
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| creator | ZHANG FENGZHI ZHAN ZHA JUN HU LINGYI |
| description | The invention discloses a synthesis method and application of hairyvein agrimony phenol F. The structure of the hairyvein agrimony phenol F is as shown in a formula (V), and the synthesis method is characterized in that a preparation method of a compound as shown in a formula (I) is carried out according to the following steps: (1) generally catalyzing by using lewis acid in an organic solvent, and carrying out condensation reaction on the compound (I) and a compound (II) to obtain a compound (III); and (2) catalyzing by using lewis acid in an organic solvent generally, and carrying out condensation reaction on the compound (IV) and the compound (III) to obtain the hairyvein agrimonol F (V). The raw materials required by the reaction are simple and easy to obtain, the conditions are mild, the reaction time is short, the atom economy is relatively high, and the operation and post-treatment are simple. The agrimonol F prepared by the method has relatively good inhibitory activity on the growth of four tumor cel |
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The structure of the hairyvein agrimony phenol F is as shown in a formula (V), and the synthesis method is characterized in that a preparation method of a compound as shown in a formula (I) is carried out according to the following steps: (1) generally catalyzing by using lewis acid in an organic solvent, and carrying out condensation reaction on the compound (I) and a compound (II) to obtain a compound (III); and (2) catalyzing by using lewis acid in an organic solvent generally, and carrying out condensation reaction on the compound (IV) and the compound (III) to obtain the hairyvein agrimonol F (V). The raw materials required by the reaction are simple and easy to obtain, the conditions are mild, the reaction time is short, the atom economy is relatively high, and the operation and post-treatment are simple. 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The structure of the hairyvein agrimony phenol F is as shown in a formula (V), and the synthesis method is characterized in that a preparation method of a compound as shown in a formula (I) is carried out according to the following steps: (1) generally catalyzing by using lewis acid in an organic solvent, and carrying out condensation reaction on the compound (I) and a compound (II) to obtain a compound (III); and (2) catalyzing by using lewis acid in an organic solvent generally, and carrying out condensation reaction on the compound (IV) and the compound (III) to obtain the hairyvein agrimonol F (V). The raw materials required by the reaction are simple and easy to obtain, the conditions are mild, the reaction time is short, the atom economy is relatively high, and the operation and post-treatment are simple. 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The structure of the hairyvein agrimony phenol F is as shown in a formula (V), and the synthesis method is characterized in that a preparation method of a compound as shown in a formula (I) is carried out according to the following steps: (1) generally catalyzing by using lewis acid in an organic solvent, and carrying out condensation reaction on the compound (I) and a compound (II) to obtain a compound (III); and (2) catalyzing by using lewis acid in an organic solvent generally, and carrying out condensation reaction on the compound (IV) and the compound (III) to obtain the hairyvein agrimonol F (V). The raw materials required by the reaction are simple and easy to obtain, the conditions are mild, the reaction time is short, the atom economy is relatively high, and the operation and post-treatment are simple. The agrimonol F prepared by the method has relatively good inhibitory activity on the growth of four tumor cel</abstract><oa>free_for_read</oa></addata></record> |
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| title | Synthesis method and application of agrimonol F |
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