Novel GDY-loaded CuBi bimetallic nano-catalyst with nano-enzyme activity for tumor treatment and preparation method of novel GDY-loaded CuBi bimetallic nano-catalyst

The invention discloses a novel GDY loaded CuBi bimetallic nano-catalyst with nano-enzyme activity for tumor treatment and a preparation method of the novel GDY loaded CuBi bimetallic nano-catalyst, and relates to the field of nano-catalysts and tumor treatment. According to the invention, graphdiyne (GDY) is used for loading CuBi nanoparticles to synthesize a bimetallic nano-material as a novel composite nano-enzyme, and the bimetallic nano-material has excellent CAT, POD and GPx-like activities, and can generate ROS in osteosarcoma cells, relieve anoxia of the osteosarcoma cells and induce copper death of the osteosarcoma cells, so that the purpose of killing the osteosarcoma cells is achieved. The invention provides a new strategy for regulating and controlling the tumor microenvironment, generating ROS and inducing copper death to treat osteosarcoma by the composite nano-enzyme. 一种具备纳米酶活性用于肿瘤治疗的新型GDY负载CuBi双金属纳米催化剂及其制备方法，涉及纳米催化剂和肿瘤治疗领域。本发明利用石墨炔(GDY)负载CuBi纳米粒子合成双金属纳米材料作为一种新型复合纳米酶，具有优良的CAT、POD、GPx样活性，可以在骨肉瘤细