Production process of medical thermoplastic polyurethane material
The invention discloses a production process of a medical thermoplastic polyurethane material, and belongs to the technical field of medical materials, polyurethane resin is prepared firstly, the polyurethane resin is polycarbonate type polyurethane with carboxyl, the carboxyl is introduced while th...
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| creator | LI TONGBING LIU YUE ZHONG RONGDONG |
| description | The invention discloses a production process of a medical thermoplastic polyurethane material, and belongs to the technical field of medical materials, polyurethane resin is prepared firstly, the polyurethane resin is polycarbonate type polyurethane with carboxyl, the carboxyl is introduced while the excellent performance of the polycarbonate type polyurethane is exerted, and the polyurethane resin is added into the polycarbonate type polyurethane; under the action of 4-dimethylaminopyridine and diisopropylcarbodiimide, carboxyl can react with hydroxyl on a heparin structure, so that heparin can be grafted on the surface of the material, and the polyurethane material can be endowed with an anticoagulant effect; the heparin is grafted in a chemical bonding mode, so that the heparin structure and the polyurethane material are combined more firmly, initial contact activation of thrombin can be hindered through an antithrombin III mediated pathway, and therefore, better anticoagulation performance is achieved.
本发 |
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| subjects | CHEMISTRY COMPOSITIONS BASED THEREON MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-UP USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS |
| title | Production process of medical thermoplastic polyurethane material |
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