3-methylthio-3-alkenyl indolone derivative and preparation method thereof

3-methylthio-3-alkenyl indolone derivative and preparation method thereof

The invention relates to the technical field of organic chemical synthesis, and particularly discloses a 3-methylthio-3-alkenyl indolone derivative and a preparation method thereof. The invention relates to a 3-methylthio-3-alkenyl indolone derivative, which is characterized in that the molecular st...

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Hauptverfasser: ZHOU SHUIPING, CHEN JIANSHUAI, PAN XINZHOU, YUAN ZIQING, SONG QIN, YU HONGSHENG, LI HAITAO, CHEN YUKUN, HUANG ZILONG
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Sprache:chi ; eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator ZHOU SHUIPING
CHEN JIANSHUAI
PAN XINZHOU
YUAN ZIQING
SONG QIN
YU HONGSHENG
LI HAITAO
CHEN YUKUN
HUANG ZILONG
description The invention relates to the technical field of organic chemical synthesis, and particularly discloses a 3-methylthio-3-alkenyl indolone derivative and a preparation method thereof. The invention relates to a 3-methylthio-3-alkenyl indolone derivative, which is characterized in that the molecular structural formula is as follows: # imgabs0 #, in the formula, R1 is one of acetyl and aryl acetyl with 7-13 carbon atoms; r2 is one of methyl, ethyl, n-propyl, isopropyl, butyl, isobutyl, tertiary butyl, allyl, benzyl, phenyl and acetyl; and R3 is one of hydrogen, fluorine, chlorine, bromine, iodine, methyl, trifluoromethyl, tertiary butyl, phenyl, methoxyl, cyano and acetoxy. The synthesis method disclosed by the invention has the advantages of high atom economy, high selectivity, high yield, unique reaction route, simple synthesis steps, good functional group tolerance and the like, and has a wide application prospect. Ketene dithioacetal is used as a methylthio reagent, and the application is carbon-sulfur bond i
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title 3-methylthio-3-alkenyl indolone derivative and preparation method thereof
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