Small molecule inhibitor of KRAS mutant protein

Compounds of formula (I) or pharmaceutically acceptable salts thereof can inhibit G12C, G12D and/or G12V mutants of Kirsteen rat sarcoma (KRAS) protein and are expected to be used, for example, as therapeutic agents for the treatment of cancer. The disclosure also provides pharmaceutical composition...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	SWAMINATHAN UMA, SLOMAN, DAVID, L, KOBAYAKAWA YU, OSHIMA TAKESHI, SCHAUF PETER, HENDERSON, TODD, GATTIACA SALVATORE, BALASTAN, IBRAHIM, HOOVER ANDY JAMES, UNO TAKAO, HAN YONGXIN, GRAHAM THOMAS H, KAWAMURA, SHUICHI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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