NO donor type composition as well as preparation method and application thereof
The invention discloses a nitric oxide donor type composition as well as a preparation method and application thereof. The composition comprises a solution A and a solution B, the solution A comprises an NO donor, a penetration enhancer, a humectant and a solvent, and the NO donor is silver nitrite...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a nitric oxide donor type composition as well as a preparation method and application thereof. The composition comprises a solution A and a solution B, the solution A comprises an NO donor, a penetration enhancer, a humectant and a solvent, and the NO donor is silver nitrite or sodium nitrite; the solution B comprises an acidic buffer solution, a penetration enhancer, a humectant and a solvent, and the pH value of the acidic buffer solution is 4.0-6.0; the mass ratio of the NO donor to the acidic buffer solution is (1-3): (1-5). The nitric oxide donor type composition has a good effect of promoting hair growth, is longer in NO release time and smaller in irritation compared with traditional acidified nitrite, and can remarkably increase the number of hair follicles and accelerate the hair follicles to enter a growth period from a resting period compared with commercially available 2% minoxidil.
本发明公开了一种一氧化氮供体型组合物及其制备方法与应用,所述组合物包括A液和B液;A液包含NO供体、促渗剂、保湿剂和溶剂,所述NO供体为亚硝酸银或亚硝酸钠;B液包含酸性缓冲液、促渗剂、 |
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