Isolated bispecific antibodies that specifically bind CD47 and PD-L1
The invention relates to the field of biotechnology and medicine, in particular to a bispecific antibody specifically binding to CD47 and PD-L1. The invention further relates to nucleic acids encoding said bispecific antibodies, expression vectors, host cells for producing said bispecific antibodies...
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| creator | LEGOTSKY SERGEY ANATOLIEVICH SABIROV ALEXEY KONSTANTINOVICH MISORIN ALEKSEY KONSTANTINOVICH VODOPINOVA, TATYANA ALEKSANDROVNA AZARIAN ADRIAN D GOLDIEV ALEKSEJ ALEKSEEVICH SOLOVYEV, VALERY VLADIMIROVICH DORONIN ALEKSANDR NIKOLAEVICH MOROZOV DMITRY VLADIMIROVICH |
| description | The invention relates to the field of biotechnology and medicine, in particular to a bispecific antibody specifically binding to CD47 and PD-L1. The invention further relates to nucleic acids encoding said bispecific antibodies, expression vectors, host cells for producing said bispecific antibodies and methods for producing said cells, pharmaceutical compositions comprising the bispecific antibodies according to the invention, and methods for producing said cells. The present invention relates to bispecific antibodies and other therapeutically active compounds, pharmaceutical compositions comprising the bispecific antibodies according to the invention and other therapeutically active compounds, methods for treating diseases or disorders mediated by CD47 and PD-L1, the use of bispecific antibodies or pharmaceutical compositions thereof for treating diseases or disorders mediated by CD47 and PD-L1, and methods for treating diseases or disorders mediated by CD47 and PD-L1. And the use of the bispecific antibodi |
| format | Patent |
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The invention further relates to nucleic acids encoding said bispecific antibodies, expression vectors, host cells for producing said bispecific antibodies and methods for producing said cells, pharmaceutical compositions comprising the bispecific antibodies according to the invention, and methods for producing said cells. The present invention relates to bispecific antibodies and other therapeutically active compounds, pharmaceutical compositions comprising the bispecific antibodies according to the invention and other therapeutically active compounds, methods for treating diseases or disorders mediated by CD47 and PD-L1, the use of bispecific antibodies or pharmaceutical compositions thereof for treating diseases or disorders mediated by CD47 and PD-L1, and methods for treating diseases or disorders mediated by CD47 and PD-L1. 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The invention further relates to nucleic acids encoding said bispecific antibodies, expression vectors, host cells for producing said bispecific antibodies and methods for producing said cells, pharmaceutical compositions comprising the bispecific antibodies according to the invention, and methods for producing said cells. The present invention relates to bispecific antibodies and other therapeutically active compounds, pharmaceutical compositions comprising the bispecific antibodies according to the invention and other therapeutically active compounds, methods for treating diseases or disorders mediated by CD47 and PD-L1, the use of bispecific antibodies or pharmaceutical compositions thereof for treating diseases or disorders mediated by CD47 and PD-L1, and methods for treating diseases or disorders mediated by CD47 and PD-L1. And the use of the bispecific antibodi</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | Isolated bispecific antibodies that specifically bind CD47 and PD-L1 |
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