Expression promoter for lipid transport gene ABCA12

The invention provides an expression promoter of a keratinocyte lipid transport gene ABCA12, and the expression promoter is amentoflavone. Preferably, the use concentration of the amentoflavone is at least 0.000625 mg/ml. The invention also relates to an application of amentoflavone in preparation of a skin external preparation with an effect of promoting the expression of a keratinocyte lipid transport gene ABCA12. Preferably, the content of the amentoflavone in the external preparation for the skin is 0.00001 to 10 weight percent. 本发明提供了一种角质形成细胞脂质运输基因ABCA12的表达促进剂，其中，所述表达促进剂是穗花杉双黄酮。优选地，穗花杉双黄酮的使用浓度至少为0.000625mg/ml。本发明还涉及穗花杉双黄酮在制备具有促进角质形成细胞脂质运输基因ABCA12的表达功效的皮肤外用剂中的应用。优选地，所述穗花杉双黄酮在皮肤外用剂中的含量为0.00001-10重量％。