Establishment method for researching traditional Chinese medicine quality markers (groups) of phlegm-reducing and cough-stopping granules for children

The invention provides a method for establishing research on traditional Chinese medicine quality markers (groups) of granules for eliminating phlegm and stopping coughing for children, which combines screening of leading components and analysis of transitional components in blood. Wherein the scree...

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Bibliographische Detailangaben
Hauptverfasser: YANG SHUYING, GAN SHIQUAN, LI FENG, TAO LING, LIU SHAOBO, LI MING, YANG NAIJIA, LI SONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a method for establishing research on traditional Chinese medicine quality markers (groups) of granules for eliminating phlegm and stopping coughing for children, which combines screening of leading components and analysis of transitional components in blood. Wherein the screening of the leading components is to carry out molecular docking screening analysis of in-vitro drug components based on general key protein targets of clinical mainly treatment symptoms of the granules for eliminating phlegm and stopping cough for children, and is combined with detection of migration components in blood, and network pharmacology and an in-vivo and in-vitro component detection technology are combined, so that the product quality is effectively and accurately evaluated and controlled. According to the establishment method disclosed by the invention, the spectrum characterization is comprehensive, the clinical effectiveness of chemical components in the product and the completeness of the quality sta