Construction method of traditional Chinese medicine disease and symptom combined ischemic stroke rat model
The invention relates to the technical field of medicines, and discloses a traditional Chinese medicine disease and syndrome combined ischemic stroke rat model construction method, which comprises the following steps: S1, selecting an SPF-level male SD rat, and adaptively feeding for one week; s2, m...
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| creator | HOU GUANQUN ZHANG WENJING HAN BINGBING LI CHONG WANG SHIJUN ZHANG YIMIN |
| description | The invention relates to the technical field of medicines, and discloses a traditional Chinese medicine disease and syndrome combined ischemic stroke rat model construction method, which comprises the following steps: S1, selecting an SPF-level male SD rat, and adaptively feeding for one week; s2, modeling by adopting loperamide hydrochloride suspension, and judging whether the model succeeds or not according to the condition of the excrement of the rat; s3, establishing an MCAO rat model for the successfully molded rat by using an improved suture method; s4, after an MCAO rat model is established, grouping is carried out, and Taojing Chengqi decoction treatment and normal saline intervention are respectively carried out; and S5, taking brain tissues and colon tissues, and detecting the content of inflammatory factors. The Yangming bowel excess ischemic stroke model is established through the rat, so that the experimental result of the model can be more accurately observed and compared with the human stroke d |
| format | Patent |
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| subjects | AGRICULTURE ANIMAL HUSBANDRY CARE OF BIRDS, FISHES, INSECTS FISHING FORESTRY HUMAN NECESSITIES HUNTING NEW BREEDS OF ANIMALS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR TRAPPING |
| title | Construction method of traditional Chinese medicine disease and symptom combined ischemic stroke rat model |
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