Benzene bridged indole carboxylic acid derivative and preparation method thereof

The invention discloses a benzene ring bridged indole carboxylic acid bidentate ligand with a novel structure and a preparation method of the benzene ring bridged indole carboxylic acid bidentate ligand, and belongs to the technical field of organic synthesis. Indole carboxylic acid which is simple and easy to obtain is used as a starting raw material, and the indole carboxylic acid derivative with a symmetrical structure is generated through three key steps of esterification reaction, coupling reaction and hydrolysis/deprotection reaction. According to the method, the raw materials are commercially available and easy to obtain, the synthesis steps are simple and efficient, the symmetrical structure product can be obtained with high yield, and a new way is provided for preparation of the compound. 本发明公开了一种新型结构的苯环桥连吲哚羧酸二齿配体及其制备方法，属于有机合成技术领域。以简单易得的吲哚羧酸作为起始原料，通过酯化反应、偶联反应和水解/脱保护反应三个关键步骤，生成了具有对称结构的吲哚羧酸衍生物。本发明方法原料均为市售易得，合成步骤简单高效，可高收率获得对称结构产物，为该类化合物制备提供了新的途径。