Novel crystal form of 1-(8-bromopyrido [2, 3-e] [1, 2, 4] triazolo [4, 3-a] pyrazine-4-yl)-n-methylazetidine-3-amine hemisuccinate

The present invention relates to a novel crystalline form of 1-(8-bromopyrido [2, 3-e] [1, 2, 4] triazolo [4, 3-a] pyrazin-4-yl)-N-methylazetidine-3-amine hemisuccinate, as well as a pharmaceutical composition comprising the same. The invention also provides the use of the novel polymorph for the treatment of diseases, such as atopic dermatitis (AD), pruritus, pruritus and various forms of urticaria, such as the chronic idiopathic urticaria subtype. 本发明涉及1-(8-溴吡啶并[2,3-e][1,2,4]三唑并[4,3-a]吡嗪-4-基)-N-甲基氮杂环丁烷-3-胺半琥珀酸盐的新晶型，以及包含它的药物组合物。本发明还提供了该新多晶型用于治疗疾病，如特应性皮炎(AD)、瘙痒、瘙痒症和各种形式的荨麻疹，例如慢性特发性荨麻疹亚型的用途。