Indanone and tetralone-ketone or hydroxyoxime as cancer therapeutic agent

Certain embodiments relate to compounds that are ER ligands, pharmaceutically acceptable salts, stereoisomers, and prodrugs thereof, in particular to such compounds that are ER [beta]-selective and/or ER [beta]-specific ligands. 某些实施方案涉及作为ER配体的化合物、其药学上可接受的盐、立体异构体及前药，特别是涉及作为ERβ选择性和/或ERβ特异性配体的此类化合物。...

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Hauptverfasser:	TIDWELL MICHAEL W, VADLAMUDI RATNA K, MCHATTIE, STANTON, ANDREW J. BRENNER
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Beschreibung
Zusammenfassung:	Certain embodiments relate to compounds that are ER ligands, pharmaceutically acceptable salts, stereoisomers, and prodrugs thereof, in particular to such compounds that are ER [beta]-selective and/or ER [beta]-specific ligands. 某些实施方案涉及作为ER配体的化合物、其药学上可接受的盐、立体异构体及前药，特别是涉及作为ERβ选择性和/或ERβ特异性配体的此类化合物。